Ataxin 1 Antibody

• Catalog number
  PA2097
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Ataxin 1
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human Predicted to work with: mouse, rat
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence in the middle region of human Ataxin 1(390-405aa TPAADLEVQQATHREA), different from the related rat sequence by two amino acids, and from the related mouse sequence by three amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Ataxin 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Ataxin 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Ataxin-1 is a protein that in humans is encoded by the ATXN1 gene. The ATXN1 gene had been mapped to 6p23 by in situ hybridization. Ataxin-1(ATXN1), a causative factor for spinocerebellar ataxia type 1(SCA1), and the related Brother of ATXN1(BOAT1) are human proteins involved in transcriptional repression. ATXN1 and BOAT1 might participate in several Notch-controlled developmental and pathological processes.
• Related articles
  1. Tong, X., Gui, H., Jin, F., Heck, B. W., Lin, P., Ma, J., Fondell, J. D., Tsai, C.-C. Ataxin-1 and brother of ataxin-1 are components of the Notch signalling pathway. EMBO Rep. 12: 428-435, 2011. 2. Volz A, Fonatsch C, Ziegler A (Jun 1992). "Regional mapping of the gene for autosomal dominant spinocerebellar ataxia (SCA1) by localizing the closely linked D6S89 locus to 6p24.2----p23.05". Cytogenet Cell Genet 60 (1): 37–9. 3. "Entrez Gene: ATXN1 ataxin 1" 4. Volz, A., Boyle, J. M., Cann, H. M., Cottingham, R. W., Orr, H. T., Ziegler, A. Report of the second international workshop on human chromosome 6. Genomics 21: 464, 1994.
• Gene Name
  ATXN1
• Protein Name
  Ataxin-1
• Gene Full Name
  ataxin 1
• Synonyms
  Ataxin-1 antibody|ATX1 antibody|ATX1_HUMAN antibody|Atxn1 antibody|D6S504E antibody|OTTHUMP00000016065 antibody|SCA1 antibody|Spinocerebellar ataxia type 1 protein antibody
• Uniprot ID
  P54253
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Ataxin  
• Gene symbol
  ATXN1L, ATXN7L1, ATXN1
• Short name
  Ataxin 1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Ataxin 1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:33279
• Gene
  ATXN1L
• Long gene name
  ataxin 1 like
• Synonyms gene name
  • ataxin 1-like
• Synonyms
  • BOAT1
• Synonyms name
  • brother of ataxin 1
• Locus
  16q22.2
• Discovery year
  2007-08-03
• Entrez gene record
  342371
• Pubmed identfication
  • 16121196
  • 17322884
  • 21475249
• RefSeq identity
  • NM_001137675.2
• VEGA ID
  OTTHUMG00000176872

Gene info

• Identity
  HGNC:22210
• Gene
  ATXN7L1
• Long gene name
  ataxin 7 like 1
• Synonyms gene
  • ATXN7L4
• Synonyms gene name
  • ataxin 7-like 4
  • ataxin 7-like 1
• Synonyms
  • KIAA1218
  • MGC33190
• GenBank acession
  • AB033044
• Locus
  7q22.3
• Discovery year
  2004-08-18
• Entrez gene record
  222255
• Pubmed identfication
  • 15115762
• VEGA ID
  OTTHUMG00000157521

Gene info

• Identity
  HGNC:10548
• Gene
  ATXN1
• Long gene name
  ataxin 1
• Synonyms gene
  • SCA1
• Synonyms gene name
  • spinocerebellar ataxia 1 (olivopontocerebellar ataxia 1, autosomal dominant, ataxin 1)
• Synonyms
  • D6S504E
  • ATX1
• GenBank acession
  • X79204
• Locus
  6p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  6310
• Pubmed identfication
  • 1582256
• RefSeq identity
  • NM_000332
• Classification
  • Ataxins
• VEGA ID
  OTTHUMG00000014303
• Locus Specific Databases
  • LRG_863

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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