AREB6 Antibody

• Catalog number
  PA1986
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  AREB6
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  mouse Predicted to work with: rat
• Analyses
  WB
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of human AREB6(108-123aa KDDECESDAENEQNHD), different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the AREB6 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The AREB6 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  ZEB1(Zinc Finger E Box-Binding Homeobox 1), also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al.(2005) demonstrated a complex(core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in cornea. Nishimura et al.(2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell(SMC) line.
• Related articles
  1. Krafchak, C. M., Pawar, H., Moroi, S. E., Sugar, A., Lichter, P. R., Mackey, D. A., Mian, S., Nairus, T., Elner, V., Schteingart, M. T., Downs, C. A., Kijek, T. G., and 9 others. Mutations in TCF8 cause posterior polymorphous corneal dystrophy and ectopic expression of COL4A3 by corneal endothelial cells. Am. J. Hum. Genet. 77: 694-708, 2005. 2. Nishimura, G., Manabe, I., Tsushima, K., Fujiu, K., Oishi, Y., Imai, Y., Maemura, K., Miyagishi, M., Higashi, Y., Kondoh, H., Nagai, R. Delta-EF1 mediates TGF-beta signaling in vascular smooth muscle cell differentiation. Dev. Cell 11: 93-104, 2006.
• Gene Name
  ZEB1
• Protein Name
  Zinc finger E-box-binding homeobox 1
• Gene Full Name
  zinc finger E-box binding homeobox 1
• Synonyms
  AREB 6 antibody|BZP antibody|Delta crystallin enhancer binding factor 1 antibody|DELTA EF1 antibody|FECD6 antibody|MGC133261 antibody|Negative regulator of IL 2 antibody|Negative regulator of IL2 antibody|NIL 2 A antibody|NIL 2 A zinc finger protein antibody|NIL 2A antibody|NIL-2-A zinc finger protein antibody|NIL2A antibody|Posterior polymorphous corneal dystrophy 3 antibody|PPCD3 antibody|Represses interleukin 2 expression antibody|TCF 8 antibody|TCF-8 antibody|TCF8 antibody|Transcription factor 8(represses interleukin 2 expression) antibody|Transcription factor 8 antibody|ZEB 1 antibody|ZEB antibody|ZEB1 antibody|ZEB1_HUMAN antibody|ZFHEP antibody|ZFHX 1A antibody|ZFHX1A antibody|Zinc finger E box binding homeobox 1 antibody|Zinc finger E-box-binding homeobox 1 antibody|Zinc finger homeodomain enhancer binding protein antibody
• Uniprot ID
  P37275
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AREB6  
• Gene symbol
  ZEB1
• Short name
  AREB6 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  AREB6 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11642
• Gene
  ZEB1
• Long gene name
  zinc finger E-box binding homeobox 1
• Synonyms gene
  • TCF8
  • PPCD3
• Synonyms gene name
  • transcription factor 8 (represses interleukin 2 expression)
  • posterior polymorphous corneal dystrophy 3
• Synonyms
  • BZP
  • ZEB
  • AREB6
  • NIL-2-A
  • Zfhep
  • Zfhx1a
  • FECD6
• GenBank acession
  • AK091478
• Locus
  10p11.22
• Discovery year
  1991-12-17
• Entrez gene record
  6935
• Pubmed identfication
  • 1427828
  • 1840704
  • 15384081
  • 16252232
• RefSeq identity
  • NM_030751
• Classification
  • ZF class homeoboxes and pseudogenes
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000017907

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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