ABCB6 Antibody

• Catalog number
  PA1723
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  ABCB6
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, rat Predicted to work with: mouse
• Analyses
  WB,IHC-P,ICC
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human ABCB6(818-842aa YADMWQLQQGQEETSEDTKPQTMER).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the ABCB6 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The ABCB6 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  ABCB6, ATP-binding cassette sub-family B member 6, mitochondrialis a protein that in humans is encoded by the ABCB6 gene. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
• Related articles
  1. Helias, V., Saison, C., Ballif, B. A., Peyrard, T., Takahashi, J., Takahashi, H., Tanaka, M., Deybach, J.-C., Puy, H., Le Gall, M., Sureau, C., Pham, B.-N., Le Pennec, P.-Y., Tani, Y., Cartron, J.-P., Arnaud, L.ABCB6 is dispensable for erythropoiesis and specifies the new blood group system Langereis.Nature Genet. 44: 170-173, 2012. 2. Krishnamurthy, P. C., Du, G., Fukuda, Y., Sun, D., Sampath, J., Mercer, K. E., Wang, J., Sosa-Pineda, B., Murti, K. G., Schuetz, J. D.Identification of a mammalian mitochondrial porphyrin transporter.Nature 443: 586-589, 2006. 3. Wang, L., He, F., Bu, J., Liu, X., Du, W., Dong, J., Cooney, J. D., Dubey, S. K., Shi, Y., Gong, B., Li, J., McBride, P. E., and 11 others.ABCB6 mutations cause ocular coloboma.Am. J. Hum. Genet. 90: 40-48, 2012.
• Gene Name
  ABCB6
• Protein Name
  ATP-binding cassette sub-family B member 6, mitochondrial
• Gene Full Name
  ATP-binding cassette, sub-family B(MDR/TAP), member 6
• Synonyms
  ABC antibody|ABC transporter umat antibody|ABC14 antibody|Abcb6 antibody|ABCB6_HUMAN antibody|ATP binding cassette sub family B member 6, mitochondrial precursor antibody|ATP binding cassette, sub family B(MDR/TAP), member 6 antibody|ATP-binding cassette sub-family B member 6 antibody|Mitochondrial ABC transporter 3 antibody|mitochondrial antibody|Mt ABC transporter 3 antibody|Mt-ABC transporter 3 antibody|MTABC3 antibody|P glycoprotein related protein antibody|P-glycoprotein-related protein antibody|PRP antibody|Ubiquitously expressed mammalian ABC half transporter antibody|Ubiquitously-expressed mammalian ABC half transporter antibody|UMAT antibody
• Uniprot ID
  Q9NP58
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ABCB6  
• Gene symbol
  ABCB6
• Short name
  ABCB6 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  ABCB6 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:47
• Gene
  ABCB6
• Long gene name
  ATP binding cassette subfamily B member 6 (Langereis blood group)
• Synonyms gene name
  • ATP-binding cassette, sub-family B (MDR/TAP), member 6
  • ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
• Synonyms
  • EST45597
  • umat
  • MTABC3
• Synonyms name
  • ATP-binding cassette half-transporter
• GenBank acession
  • AF070598
• Locus
  2q35
• Discovery year
  1999-10-26
• Entrez gene record
  10058
• Pubmed identfication
  • 8894702
  • 9110174
• RefSeq identity
  • NM_005689
• Classification
  • ATP binding cassette subfamily B
  • Blood group antigens
• VEGA ID
  OTTHUMG00000133131
• Locus Specific Databases
  • LRG_824

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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