Recombinant Mouse Low Affinity IgG Fc Receptor IV/FcgR4/CD16-2 (C-6His)

• Catalog number
  CS21
• Price
  Please ask
• Size
  10ug

• Alternative names
  Low Affinity Immunoglobulin Gamma Fc Region Receptor IV;FcgR4; CD16-2
• Description
  Recombinant Mouse Low Affinity Immunoglobulin Gamma Fc Region Receptor IV is produced by our Mammalian expression system and the target gene encoding Gly21-Gln203 is expressed with a 6His tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-His
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  Q8R2R4
• TargetSequence
  Gly21-Gln203
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
• Note
  For research use only.
• Test
  A high affinity purification column was use to purify Recombinant Mouse IgG Fc Receptor IV/FcgR4/CD16-2 (C-6His) by Bon Opus by chromatographic size exclusion. Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• About
  Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures.
• Latin name
  Mus musculus
• Additional description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Receptor   IV/FcgR4/CD16-2   C-6His  
• Gene symbol
  SELPLG, FCGR3A, FCGR3B, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2, RNU6-2
• Short name
  Recombinant Mouse IgG Fc Receptor IV/FcgR4/CD16-2 (C-6His)
• Technique
  Recombinant, affinity, Mouse, IgG, FC, IgGs, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Host
  mouse
• Isotype
  IgG, IgG
• Species
  Mouse, Mouses
• Alternative name
  Rec. Mouse Low protein Immunoglobulin G fragment c Receptor IV/FcgR4/CD16-2 (C-6His)
• Alternative technique
  rec, murine, immunoglobulins

Gene info

• Identity
  HGNC:10722
• Gene
  SELPLG
• Long gene name
  selectin P ligand
• Synonyms
  • PSGL-1
  • CD162
• Locus
  12q24.11
• Discovery year
  1995-01-31
• Entrez gene record
  6404
• Pubmed identfication
  • 7505206
• Classification
  • Receptor ligands
  • CD molecules
• VEGA ID
  OTTHUMG00000169411

Gene info

• Identity
  HGNC:3619
• Gene
  FCGR3A
• Long gene name
  Fc gamma receptor IIIa
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Fc fragment of IgG receptor IIIa
• Synonyms
  • CD16
  • CD16a
  • FcgammaRIIIa
  • FcGRIIIA
• GenBank acession
  • BC036723
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2214
• Pubmed identfication
  • 2139735
  • 11835346
  • 19309690
• RefSeq identity
  • NM_000569
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034466
• Locus Specific Databases
  • FCGR3Abase: Mutation registry for Natural killer cell deficiency
  • LRG_60

Gene info

• Identity
  HGNC:3620
• Gene
  FCGR3B
• Long gene name
  Fc gamma receptor IIIb
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG receptor IIIb
• Synonyms
  • CD16
  • CD16b
  • FcgammaRIIIb
  • FcRIIIb
• GenBank acession
  • J04162
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2215
• Pubmed identfication
  • 2139735
  • 11034564
  • 17529978
• RefSeq identity
  • NM_000570
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000074099
• Locus Specific Databases
  • LRG_1238

Gene info

• Identity
  HGNC:35282
• Gene
  MIR1289-2
• Long gene name
  microRNA 1289-2
• Synonyms gene
  • MIRN1289-2
• Synonyms
  • hsa-mir-1289-2
• Locus
  5q31.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302134
• RefSeq identity
  • NR_031621
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:32113
• Gene
  MIR521-2
• Long gene name
  microRNA 521-2
• Synonyms gene
  • MIRN521-2
• Synonyms
  • hsa-mir-521-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574481
• RefSeq identity
  • NR_030203
• Classification
  • MicroRNA MIR515 family

Gene info

• Identity
  HGNC:33641
• Gene
  MIR509-2
• Long gene name
  microRNA 509-2
• Synonyms gene
  • MIRN509-2
• Synonyms
  • hsa-mir-509-2
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126301
• RefSeq identity
  • NR_030586
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:32091
• Gene
  MIR512-2
• Long gene name
  microRNA 512-2
• Synonyms gene
  • MIRN512-2
• Synonyms
  • hsa-mir-512-2
• Locus
  19q13.42
• Discovery year
  2005-07-15
• Entrez gene record
  574459
• RefSeq identity
  • NR_030181
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31639
• Gene
  MIR7-2
• Long gene name
  microRNA 7-2
• Synonyms gene
  • MIRN7-2
• Synonyms
  • hsa-mir-7-2
• Locus
  15q26.1
• Discovery year
  2004-04-23
• Entrez gene record
  407044
• RefSeq identity
  • NR_029606
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:32051
• Gene
  MIR329-2
• Long gene name
  microRNA 329-2
• Synonyms gene
  • MIRN329-2
• Synonyms
  • hsa-mir-329-2
• Locus
  14q32.31
• Discovery year
  2005-07-11
• Entrez gene record
  574409
• RefSeq identity
  • NR_029968
• Classification
  • MicroRNA MIR329 family

Gene info

• Identity
  HGNC:34270
• Gene
  RNU6-2
• Long gene name
  RNA, U6 small nuclear 2
• Synonyms
  • U6-2
• Locus
  19p13.3
• Discovery year
  2008-06-10
• Entrez gene record
  103625684
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_125730
• Classification
  • Small nuclear RNAs

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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