Recombinant Mouse Growth Hormone Receptor/GHR/GHBP (C-Fc)
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Catalog number
CM02
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Price
Please ask
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Size
1mg
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Alternative names
Growth hormone receptor, Ghr, Growth Hormone R
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Description
Recombinant Mouse Growth Hormone receptor is produced by our Mammalian expression system and the target gene encoding Met1-Gln273 is expressed with a Fc tag at the C-terminus.
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Expression
Human Cells
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Tag
C-Fc
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug)
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Accession
Q3UP14
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TargetSequence
Met1-Gln273
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Shipping
Ambient
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Formulation
Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
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Note
For research use only.
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Additional description
Hormone releasing factors and releasing hormones are signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
GHR
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Short name
Recombinant Mouse Growth Hormone Receptor/GHR/GHBP (C-Fc)
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Technique
Recombinant, Mouse, FC, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
mouse
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Species
Mouse, Mouses
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Alternative name
Rec. Mouse Growth Hormone Receptor/growth hormone receptor/GHBP (C-fragment c)
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Alternative technique
rec, murine
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Alternative to gene target
growth hormone receptor, GHBP, GHR and IDBG-18930 and ENSG00000112964 and 2690, proline-rich region binding, nuclei, Ghr and IDBG-127871 and ENSMUSG00000055737 and 14600, GHR and IDBG-629685 and ENSBTAG00000001335 and 280805
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Gene info
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Identity
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Gene
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Long gene name
growth hormone receptor
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Synonyms
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Synonyms name
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Locus
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Discovery year
1989-06-30
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Entrez gene record
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RefSeq identity
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Classification
- Fibronectin type III domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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