Recombinant Human Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (C-6His)
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Catalog number
CI39
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Price
Please ask
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Size
10ug
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Alternative names
Tumor necrosis factor receptor superfamily member 1B，Tumor necrosis factor receptor 2，Tumor necrosis factor receptor type II，p75，p80 TNF-alpha receptor，TBP-2，TBPII，TNFRSF1B，TNFBR, TNFR2
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Description
Recombinant Human Tumor Necrosis Factor Receptor II is produced by our Mammalian expression system and the target gene encoding Leu23-Asp257 is expressed with a 6His tag at the C-terminus.
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Expression
Human Cells
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Tag
C-His
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Endotoxin
Less than 0.1 ng/ug (1 EU/ug)
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Accession
P20333
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TargetSequence
Leu23-Asp257
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Shipping
Ambient
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Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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Note
For research use only.
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Additional description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TNFRSF1B
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Short name
Recombinant Tumor Necrosis Factor Receptor II/TNFRSF1B/CD120b (C-6His)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Rec. H. sapiens Tumor Necrosis Factor Receptor II/tumor necrosis factor receptor superfamily, member 1B/CD120b (C-6His)
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Alternative technique
rec
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 1B, CD120b and p75 and p75TNFR and TBPII and TNF-R-II and TNF-R75 and TNFBR and TNFR1B and TNFR2 and TNFR80, TNFRSF1B and IDBG-90091 and ENSG00000028137 and 7133, ubiquitin protein ligase binding, nuclei, Tnfrsf1b and IDBG-203277 and ENSMUSG00000028599 and 21938, TNFRSF1B and IDBG-632369 and ENSBTAG00000024928 and 338033
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Tissue
tumor
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Gene info
MeSH Data
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Name
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Concept
Scope note:
A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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