Recombinant Human Receptor Tyrosine-Protein Kinase ErbB-3/HER3 (C-Fc)
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Catalog numberCX93
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PricePlease ask
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Size1mg
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Alternative namesProto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Her3
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DescriptionRecombinant Human ErbB3 is produced by our Mammalian expression system and the target gene encoding Ser20-Cys331 is expressed with a Fc tag at the C-terminus.
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ExpressionHuman Cells
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TagC-Fc
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EndotoxinLess than 0.1 ng/ug (1 EU/ug)
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AccessionP21860
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TargetSequenceSer20-Cys331
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ShippingAmbient
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FormulationLyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
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NoteFor research use only.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional descriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolERBB3
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Short nameRecombinant Receptor Tyrosine-Protein Kinase ErbB-3/HER3 (C-Fc)
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TechniqueRecombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRec. H. sapiens Receptor Tyrosine-Protein phosphorylation catalyst ErbB-3/HER3 (C-fragment c)
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameerb-b2 receptor tyrosine kinase 3
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Synonyms gene
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Synonyms gene name
- lethal congenital contracture syndrome 2
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-07-15
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Entrez gene record
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RefSeq identity
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Classification
- Erb-b2 receptor tyrosine kinases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data