Recombinant Human Platelet Receptor Gi24/VISTA/B7-H5/PD-1H (C-mFC)

• Catalog number
  CW24
• Price
  Please ask
• Size
  1mg

• Alternative names
  Platelet receptor Gi24;Stress-induced secreted protein-1;Sisp-1;C10orf54;SISP1
• Description
  Recombinant Human Platelet Receptor Gi24 is produced by our Mammalian expression system and the target gene encoding Phe33-Ala194 is expressed with a mFc tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-mFc
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  Q9H7M9
• TargetSequence
  Phe33-Ala194
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
• Note
  For research use only.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional description
  Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Platelet   Receptor   Gi24/VISTA/B7-H5/PD-1H   C-mFC  
• Gene symbol
  VSIR, HHLA2, CD274, PDCD1LG2, NME5, RNY4P2, LRRC23, ENPP2, PCDHGB7, NCR3LG1
• Short name
  Recombinant Platelet Receptor Gi24/VISTA/B7-H5/PD-1H (C-mFC)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Platelet Receptor Gi24/VISTA/B7-H5/PD-1H (C-mFC)
• Alternative technique
  rec

Gene info

• Identity
  HGNC:30085
• Gene
  VSIR
• Long gene name
  V-set immunoregulatory receptor
• Synonyms gene
  • C10orf54
• Synonyms gene name
  • chromosome 10 open reading frame 54
• Synonyms
  • SISP1
  • GI24
  • B7-H5
  • B7H5
  • VISTA
  • PD-1H
  • Dies1
• Synonyms name
  • stress induced secreted protein 1
  • V-domain Ig suppressor of T cell activation
  • PDCD1 homolog
• GenBank acession
  • AF193048
• Locus
  10q22.1
• Discovery year
  2005-10-06
• Entrez gene record
  64115
• Pubmed identfication
  • 12975309
  • 24691993
  • 25279955
• RefSeq identity
  • NM_022153
• Classification
  • B7 family
  • V-set domain containing
• VEGA ID
  OTTHUMG00000018426

Gene info

• Identity
  HGNC:4905
• Gene
  HHLA2
• Long gene name
  HERV-H LTR-associating 2
• Synonyms
  • B7H7
  • B7-H5
  • B7y
  • B7-H7
• GenBank acession
  • AF126162
• Locus
  3q13.13
• Discovery year
  1999-09-07
• Entrez gene record
  11148
• Pubmed identfication
  • 10444326
  • 23784006
  • 22488247
• RefSeq identity
  • NM_007072
• Classification
  • C1-set domain containing
  • V-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000159224

Gene info

• Identity
  HGNC:17635
• Gene
  CD274
• Long gene name
  CD274 molecule
• Synonyms gene
  • PDCD1LG1
• Synonyms gene name
  • programmed cell death 1 ligand 1
  • CD274 antigen
• Synonyms
  • B7-H
  • B7H1
  • PD-L1
  • PDL1
  • B7-H1
• Synonyms name
  • B7 homolog 1
• GenBank acession
  • AF177937
• Locus
  9p24.1
• Discovery year
  2003-11-13
• Entrez gene record
  29126
• Pubmed identfication
  • 11015443
  • 10581077
• RefSeq identity
  • NM_014143
• Classification
  • Receptor ligands
  • C2-set domain containing
  • V-set domain containing
  • B7 family
  • CD molecules
• VEGA ID
  OTTHUMG00000019503

Gene info

• Identity
  HGNC:18731
• Gene
  PDCD1LG2
• Long gene name
  programmed cell death 1 ligand 2
• Synonyms
  • PD-L2
  • Btdc
  • PDL2
  • bA574F11.2
  • CD273
  • B7-DC
• Synonyms name
  • B7 dendritic cell molecule
• GenBank acession
  • AF344424
• Locus
  9p24.1
• Discovery year
  2003-11-14
• Entrez gene record
  80380
• Pubmed identfication
  • 11224527
• RefSeq identity
  • NM_025239
• Classification
  • B7 family
  • CD molecules
  • Immunoglobulin like domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000019504

Gene info

• Identity
  HGNC:7853
• Gene
  NME5
• Long gene name
  NME/NM23 family member 5
• Synonyms gene name
  • non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
• Synonyms
  • nm23-H5
  • RSPH23
• Synonyms name
  • radial spoke 23 homolog (Chlamydomonas)
• GenBank acession
  • Y14992
• Locus
  5q31.2
• Discovery year
  1998-02-26
• Entrez gene record
  8382
• Pubmed identfication
  • 9742940
  • 19852809
• RefSeq identity
  • NM_003551
• Classification
  • NME/NM23 family
• VEGA ID
  OTTHUMG00000129207

Gene info

• Identity
  HGNC:10246
• Gene
  RNY4P2
• Long gene name
  RNY4 pseudogene 2
• Synonyms gene name
  • RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
  • RNA, Ro-associated Y4 pseudogene 2
• Synonyms
  • hY4.B7
• GenBank acession
  • M77130
• Locus
  17q21.31
• Discovery year
  1993-08-25
• Entrez gene record
  6088
• RefSeq identity
  • NG_005037

Gene info

• Identity
  HGNC:19138
• Gene
  LRRC23
• Long gene name
  leucine rich repeat containing 23
• Synonyms
  • B7
  • LRPB7
• GenBank acession
  • BC014450
• Locus
  12p13.31
• Discovery year
  2006-01-24
• Entrez gene record
  10233
• Pubmed identfication
  • 11830501
  • 11826754
• RefSeq identity
  • NM_006992
• VEGA ID
  OTTHUMG00000156668

Gene info

• Identity
  HGNC:3357
• Gene
  ENPP2
• Long gene name
  ectonucleotide pyrophosphatase/phosphodiesterase 2
• Synonyms gene
  • PDNP2
• Synonyms
  • ATX
  • PD-IALPHA
• Synonyms name
  • autotaxin
• GenBank acession
  • D45421
• Locus
  8q24.12
• Discovery year
  1995-08-10
• Entrez gene record
  5168
• Pubmed identfication
  • 8586446
• Classification
  • Ectonucleotide pyrophosphatase/phosphodiesterase family
• VEGA ID
  OTTHUMG00000164995

Gene info

• Identity
  HGNC:8714
• Gene
  PCDHGB7
• Long gene name
  protocadherin gamma subfamily B, 7
• Synonyms
  • ME6
  • PCDH-GAMMA-B7
• Synonyms name
  • cadherin ME6
• GenBank acession
  • AF152523
• Locus
  5q31.3
• Discovery year
  2000-06-28
• Entrez gene record
  56099
• Pubmed identfication
  • 10380929
• RefSeq identity
  • NM_018927
• Classification
  • Clustered protocadherins
• VEGA ID
  OTTHUMG00000164054

Gene info

• Identity
  HGNC:42400
• Gene
  NCR3LG1
• Long gene name
  natural killer cell cytotoxicity receptor 3 ligand 1
• Synonyms
  • DKFZp686O24166
  • B7-H6
• Synonyms name
  • B7 homolog 6
• Locus
  11p15.1
• Discovery year
  2012-04-12
• Entrez gene record
  374383
• Pubmed identfication
  • 19528259
• RefSeq identity
  • NM_001202439
• Classification
  • Receptor ligands
  • C1-set domain containing
  • B7 family
• VEGA ID
  OTTHUMG00000165913

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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