Recombinant Human PD-L1/B7-H1/CD274 (C-mFc)

Alternative names

Programmed Cell Death 1 Ligand 1, PD-L1, PDCD1 Ligand 1, Programmed Death Ligand 1, B7 Homolog 1, B7-H1, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Description

Recombinant Human Programmed Cell Death 1 Ligand 1 is produced by our Mammalian expression system and the target gene encoding Phe19-Thr239 is expressed with a mFc tag at the C-terminus.
Expression

Human Cells
Tag

C-mFc
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

Q9NZQ7
TargetSequence

Phe19-Thr239
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

PD-L1/B7-H1/CD274 C-mFc
Gene symbol

CD274, PDCD1LG2, VSIR, H1-9P, HHLA2, RLN1, H1-8, RNY4P2, LRRC23, ENPP2
Short name

Recombinant PD-L1/B7-H1/CD274 (C-mFc)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens PD-L1/B7-H1/CD274 molecule (C-mFc)
Alternative technique

rec
Alternative to gene target

CD274 molecule, CD274 and IDBG-47487 and ENSG00000120217 and 29126, protein binding, Cell surfaces, Cd274 and IDBG-157249 and ENSMUSG00000016496 and 60533, PD-L1 and IDBG-631351 and ENSBTAG00000000095 and 533834

Identity

HGNC:18731
Gene

PDCD1LG2
Long gene name

programmed cell death 1 ligand 2
Synonyms
- PD-L2
- Btdc
- PDL2
- bA574F11.2
- CD273
- B7-DC
Synonyms name
- B7 dendritic cell molecule
GenBank acession
- AF344424
Locus

9p24.1
Discovery year

2003-11-14
Entrez gene record

80380
Pubmed identfication
- 11224527
RefSeq identity
- NM_025239
Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
VEGA ID

OTTHUMG00000019504

Identity

HGNC:30616
Gene

H1-9P
Long gene name

H1.9 linker histone, pseudogene
Synonyms gene
- HILS1
- H1-9
Synonyms gene name
- histone linker H1 domain, spermatid-specific 1
- histone linker H1 domain, spermatid-specific 1 (pseudogene)
- H1.9 linker histone (pseudogene)
Synonyms
- H1.9
GenBank acession
- AY286318
Locus

17q21.33
Discovery year

2005-12-16
Entrez gene record

373861
Pubmed identfication
- 12920187
- 30068355
RefSeq identity
- NR_024193
Classification
- H1 histones
VEGA ID

OTTHUMG00000162025

Identity

HGNC:18463
Gene

H1-8
Long gene name

H1.8 linker histone
Synonyms gene
- H1FOO
Synonyms gene name
- H1 histone family, member O, oocyte-specific
- H1 histone family member O oocyte specific
GenBank acession
- AY158091
Locus

3q22.1
Discovery year

2003-05-23
Entrez gene record

132243
Pubmed identfication
- 12408966
RefSeq identity
- NM_153833
Classification
- H1 histones
VEGA ID

OTTHUMG00000159541

Identity

HGNC:10246
Gene

RNY4P2
Long gene name

RNY4 pseudogene 2
Synonyms gene name
- RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
- RNA, Ro-associated Y4 pseudogene 2
Synonyms
- hY4.B7
GenBank acession
- M77130
Locus

17q21.31
Discovery year

1993-08-25
Entrez gene record

6088
RefSeq identity
- NG_005037

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data