Recombinant Human Hepatocyte Growth Factor Receptor/HGF R/cMet (C-6His)

• Catalog number
  CS56
• Price
  Please ask
• Size
  1mg

• Alternative names
  Hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; Proto-oncogene c-Met; Scatter factor receptor; SF receptor; Tyrosine-protein kinase Met; MET
• Description
  Recombinant Human Hepatocyte Growth Factor Receptor is produced by our Mammalian expression system and the target gene encoding Glu25-Thr932 is expressed with a 6His tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-His
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  P08581
• TargetSequence
  Glu25-Thr932
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
• Note
  For research use only.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Hepatocyte   Growth   Factor   Receptor/HGF   R/cMet   C-6His  
• Gene symbol
  SOS1, HGF, IL6
• Short name
  Recombinant Hepatocyte Growth Factor Receptor/HGF R/cMet (C-6His)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens Hepatocyte Growth Factor Receptor/hepatocyte growth factor (hepapoietin A; scatter factor) R/cMet (C-6His)
• Alternative technique
  rec
• Alternative to gene target
  hepatocyte growth factor (hepapoietin A; scatter factor), DFNB39 and F-TCF and HGFB and HPTA and SF, HGF and IDBG-24150 and ENSG00000019991 and 3082, protein heterodimerization activity, Extracellular, Hgf and IDBG-136449 and ENSMUSG00000028864 and 15234, HGF and IDBG-631194 and ENSBTAG00000017664 and 282879

Gene info

• Identity
  HGNC:11187
• Gene
  SOS1
• Long gene name
  SOS Ras/Rac guanine nucleotide exchange factor 1
• Synonyms gene
  • GINGF
• Synonyms gene name
  • gingival fibromatosis, hereditary, 1
  • son of sevenless homolog 1 (Drosophila)
• Synonyms
  • HGF
  • GF1
• GenBank acession
  • L13857
• Locus
  2p22.1
• Discovery year
  1993-10-27
• Entrez gene record
  6654
• Pubmed identfication
  • 8276400
  • 10995566
• RefSeq identity
  • NM_005633
• Classification
  • Dbl family Rho GEFs
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000102109
• Locus Specific Databases
  • LRG_754

Gene info

• Identity
  HGNC:4893
• Gene
  HGF
• Long gene name
  hepatocyte growth factor
• Synonyms gene
  • DFNB39
• Synonyms gene name
  • deafness, autosomal recessive 39
  • hepatocyte growth factor (hepapoietin A; scatter factor)
• Synonyms
  • SF
  • F-TCF
  • HGFB
  • HPTA
• Synonyms name
  • hepatopoietin A
  • fibroblast-derived tumor cytotoxic factor
  • scatter factor
  • lung fibroblast-derived mitogen
• Locus
  7q21.11
• Discovery year
  1991-06-07
• Entrez gene record
  3082
• Pubmed identfication
  • 1837206
  • 19576567
• RefSeq identity
  • NM_000601
• VEGA ID
  OTTHUMG00000023804

Gene info

• Identity
  HGNC:6018
• Gene
  IL6
• Long gene name
  interleukin 6
• Synonyms gene
  • IFNB2
• Synonyms gene name
  • interleukin 6 (interferon, beta 2)
• Synonyms
  • IL-6
  • BSF2
  • HGF
  • HSF
• Synonyms name
  • interferon, beta 2
• GenBank acession
  • M18403
• Locus
  7p15.3
• Discovery year
  1986-01-01
• Entrez gene record
  3569
• Pubmed identfication
  • 3294161
• RefSeq identity
  • NM_000600
• Classification
  • Interleukins
  • Interferons
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000023178

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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