Recombinant Human CA125 (C-6His)

Alternative names

CA125 ovarian cancer antigen; CA125; CA-125; CA125MUC-16; FLJ14303; MUC16; mucin 16, cell surface associated; mucin-16
Description

Recombinant Human Mucin-16 is produced by our Mammalian expression system and the target gene encoding Gly12660-Met12923 is expressed with a 6His tag at the C-terminus.
Expression

Human 293 Cells
Tag

C-His
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

Q8WXI7
TargetSequence

Gly12660-Met12923
Shipping

Ambient
Formulation

Lyophilized from a 0.2 um filtered solution of 50 mM Tris, 100 mM Glycine, pH 7.5.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

CA125 C-6His
Gene symbol

MUC16, NBR1
Short name

Recombinant CA125 (C-6His)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens CA125 (C-6His)
Alternative technique

rec

Identity

HGNC:6746
Gene

NBR1
Long gene name

NBR1 autophagy cargo receptor
Synonyms gene
- M17S2
Synonyms gene name
- membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)
- neighbor of BRCA1 gene 1
Synonyms
- CA125
- KIAA0049
- 1A1-3B
GenBank acession
- X76952
Locus

17q21.31
Discovery year

1994-08-29
Entrez gene record

4077
Pubmed identfication
- 8069304
- 26112016
RefSeq identity
- NM_005899
Classification
- Zinc fingers ZZ-type
VEGA ID

OTTHUMG00000180878

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data