Recombinant Human B7 Homolog 4/B7-H4/VTCN1 (C-mFC)

Alternative names

B7S1; B7x; Vtcn1; B7h.5; B7-H4; B7H4T-cell costimulatory molecule B7x; B7S1VCTN1; B7XPRO1291; FLJ22418; Immune costimulatory protein B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1; V-set domain-containing T-cell activation inhibitor 1
Description

Recombinant Human B7 Homolog 4 is produced by our Mammalian expression system and the target gene encoding Phe29-Ala258 is expressed with a mFc tag at the C-terminus.
Expression

Human Cells
Tag

C-mFc
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

Q7Z7D3
TargetSequence

Phe29-Ala258
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Homolog 4/B7-H4/VTCN1 C-mFC
Gene symbol

VTCN1, H4C6, HHLA2, H4C13, RNY4P2, LRRC23, H4C8, PCDHGB7, NCR3LG1, CD274
Short name

Recombinant B7 Homolog 4/B7-H4/VTCN1 (C-mFC)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens B7 Homolog 4/B7-H4/V-set domain containing T cellular activation inhibitor 1 (C-mFC)
Alternative technique

rec
Alternative to gene target

V-set domain containing T cell activation inhibitor 1, VTCN1 and IDBG-101440 and ENSG00000134258 and 79679, protein binding, Cell surfaces, Vtcn1 and IDBG-179327 and ENSMUSG00000051076 and 242122, VTCN1 and IDBG-634392 and ENSBTAG00000014466 and 539919

Identity

HGNC:4783
Gene

H4C6
Long gene name

H4 clustered histone 6
Synonyms gene
- H4FC
- HIST1H4F
Synonyms gene name
- H4 histone family, member C
- histone 1, H4f
- histone cluster 1, H4f
- histone cluster 1 H4 family member f
Synonyms
- H4/c
- H4
GenBank acession
- M60749
Locus

6p22.2
Discovery year

1998-09-07
Entrez gene record

8361
Pubmed identfication
- 1916825
- 9119399
- 12408966
RefSeq identity
- NM_003540
Classification
- H4 histones
VEGA ID

OTTHUMG00000014443

Identity

HGNC:4791
Gene

H4C13
Long gene name

H4 clustered histone 13
Synonyms gene
- H4FK
- HIST1H4L
Synonyms gene name
- H4 histone family, member K
- histone 1, H4l
- histone cluster 1, H4l
- histone cluster 1 H4 family member l
Synonyms
- H4.k
- H4/k
GenBank acession
- X83548
Locus

6p22.1
Discovery year

1998-09-07
Entrez gene record

8368
Pubmed identfication
- 9031620
- 9439656
- 12408966
RefSeq identity
- NM_003546
Classification
- H4 histones
VEGA ID

OTTHUMG00000016211

Identity

HGNC:10246
Gene

RNY4P2
Long gene name

RNY4 pseudogene 2
Synonyms gene name
- RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
- RNA, Ro-associated Y4 pseudogene 2
Synonyms
- hY4.B7
GenBank acession
- M77130
Locus

17q21.31
Discovery year

1993-08-25
Entrez gene record

6088
RefSeq identity
- NG_005037

Identity

HGNC:4788
Gene

H4C8
Long gene name

H4 clustered histone 8
Synonyms gene
- H4FH
- HIST1H4H
Synonyms gene name
- H4 histone family, member H
- histone 1, H4h
- histone cluster 1, H4h
- histone cluster 1 H4 family member h
Synonyms
- H4/h
GenBank acession
- X60487
Locus

6p22.2
Discovery year

1998-09-07
Entrez gene record

8365
Pubmed identfication
- 9119399
- 12408966
RefSeq identity
- NM_003543
Classification
- H4 histones
VEGA ID

OTTHUMG00000014454

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data