Recombinant Human B7-1/CD80 (C-mFC)

Alternative names

CD80; Activation B7-1 antigen; B7; BB1; CD28LG1; CD28LGB7-1 antigen; T-lymphocyte activation antigen CD80
Description

Recombinant Human Activation B7-1 Antigen is produced by our Mammalian expression system and the target gene encoding Val35-Leu242 is expressed with a mFc tag at the C-terminus.
Expression

Human Cells
Tag

C-mFc
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

P33681
TargetSequence

Val35-Leu242
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

B7-1/CD80 C-mFC
Gene symbol

CD80, HHLA2, RNY4P2, LRRC23, PCDHGB7, NCR3LG1, CD274, CD86, TLX1NB, CD276
Short name

Recombinant B7-1/CD80 (C-mFC)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens B7-1/CD80 molecule (C-mFC)
Alternative technique

rec
Alternative to gene target

CD80 molecule, B7 and B7-1 and B7.1 and BB1 and CD28LG and CD28LG1 and LAB7, CD80 and IDBG-51287 and ENSG00000121594 and 941, coreceptor activity, Cell surfaces, Cd80 and IDBG-160288 and ENSMUSG00000075122 and 12519, BT.27986 and IDBG-632750 and ENSBTAG00000018059 and 407131

Identity

HGNC:1700
Gene

CD80
Long gene name

CD80 molecule
Synonyms gene
- CD28LG
- CD28LG1
Synonyms gene name
- CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)
- CD80 molecule
Synonyms
- B7.1
- B7-1
Synonyms name
- B-lymphocyte activation antigen B7
Locus

3q13.33
Discovery year

1993-12-14
Entrez gene record

941
Pubmed identfication
- 1370389
RefSeq identity
- NM_005191
Classification
- B7 family
- CD molecules
- C2-set domain containing
- V-set domain containing
VEGA ID

OTTHUMG00000159419

Identity

HGNC:10246
Gene

RNY4P2
Long gene name

RNY4 pseudogene 2
Synonyms gene name
- RNA, Y4 small cytoplasmic (associated with Ro protein) pseudogene 2
- RNA, Ro-associated Y4 pseudogene 2
Synonyms
- hY4.B7
GenBank acession
- M77130
Locus

17q21.31
Discovery year

1993-08-25
Entrez gene record

6088
RefSeq identity
- NG_005037

Identity

HGNC:19137
Gene

CD276
Long gene name

CD276 molecule
Synonyms gene name
- CD276 antigen
Synonyms
- B7-H3
- B7H3
- B7RP-2
GenBank acession
- AF302102
Locus

15q24.1
Discovery year

2005-03-04
Entrez gene record

80381
Pubmed identfication
- 11224528
- 12055244
RefSeq identity
- NM_025240
Classification
- C2-set domain containing
- V-set domain containing
- B7 family
- CD molecules
VEGA ID

OTTHUMG00000137585

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data