Recombinant Human B-cell Receptor CD22/Siglec-2/CD22 (C-Fc）

• Catalog number
  CC09
• Price
  Please ask
• Size
  1mg

• Alternative names
  B-cell receptor CD22; BL-CAM; B-lymphocyte cell adhesion molecule; CD22 antigenMGC130020; CD22 molecule; CD22; sialic acid binding Ig-like lectin 2; Siglec-2; SIGLEC2FLJ22814; T-cell surface antigen Leu-14
• Description
  Recombinant Human B-cell Receptor CD22 is produced by our Mammalian expression system and the target gene encoding Asp20-Arg687 is expressed with a Fc tag at the C-terminus.
• Expression
  Human Cells
• Tag
  C-Fc
• Endotoxin
  Less than 0.1 ng/ug (1 EU/ug)
• Accession
  P20273
• TargetSequence
  Asp20-Arg687
• Shipping
  Ambient
• Formulation
  Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
• Note
  For research use only.
• Additional description
  For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Receptor   CD22/Siglec-2/CD22   C-Fc）  
• Gene symbol
  CD22
• Short name
  Recombinant B- Receptor CD22/Siglec-2/CD22 (C-Fc）
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Rec. H. sapiens B-cellular Receptor CD22 molecule/Siglec-2/CD22 molecule (C-fragment c）
• Alternative technique
  rec
• Alternative to gene target
  CD22 molecule, SIGLEC-2 and SIGLEC2, CD22 and IDBG-44001 and ENSG00000012124 and 933, protein binding, Cell surfaces, Cd22 and IDBG-171574 and ENSMUSG00000030577 and 12483, CD22 and IDBG-635610 and ENSBTAG00000011887 and 514582
• Tissue
  cell

Gene info

• Identity
  HGNC:1643
• Gene
  CD22
• Long gene name
  CD22 molecule
• Synonyms gene name
  • CD22 antigen
• Synonyms
  • SIGLEC-2
  • SIGLEC2
• Synonyms name
  • sialic acid binding Ig-like lectin 2
• GenBank acession
  • X52785
• Locus
  19q13.12
• Discovery year
  1991-06-06
• Entrez gene record
  933
• Pubmed identfication
  • 8496602
  • 1691828
• RefSeq identity
  • NM_001771
• Classification
  • CD molecules
  • MicroRNA protein coding host genes
  • C2-set domain containing
  • Sialic acid binding Ig like lectins
• VEGA ID
  OTTHUMG00000183298

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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