Recombinant Human α-Synuclein/SNCA

Alternative names

Alpha-Synuclein, Non-A Beta Component of AD Amyloid, Non-A4 Component of Amyloid Precursor, NACP, SNCA, NACP, PARK1
Description

Recombinant Human alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.
Expression

E. coli
Tag

tag free
Endotoxin

Less than 0.1 ng/ug (1 EU/ug)
Accession

P37840
TargetSequence

Met1-Ala140
Shipping

Ambient
Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Note

For research use only.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

α-Synuclein/SNCA
Gene symbol

SNCA-AS1, SNCA
Short name

Recombinant α-Synuclein/SNCA
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Bon Opus advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Species

Human, Humans
Alternative name

Rec. H. sapiens α-Synuclein/synuclein, alpha (non A4 component on amyloid precursor)
Alternative technique

rec
Alternative to gene target

synuclein, alpha (non A4 component of amyloid precursor), NACP and PARK1 and PARK4 and PD1, SNCA and IDBG-30077 and ENSG00000145335 and 6622, phosphoprotein binding, nuclei, Snca and IDBG-152558 and ENSMUSG00000025889 and 20617, SNCA and IDBG-641103 and ENSBTAG00000024957 and 282857

Identity

HGNC:11138
Gene

SNCA
Long gene name

synuclein alpha
Synonyms gene
- PARK1
- PARK4
Synonyms gene name
- Parkinson disease (autosomal dominant, Lewy body) 4
- synuclein, alpha (non A4 component of amyloid precursor)
Synonyms
- NACP
- PD1
Synonyms name
GenBank acession
- L08850
Locus

4q22.1
Discovery year

1995-01-24
Entrez gene record

6622
Pubmed identfication
- 8248242
- 14593171
VEGA ID

OTTHUMG00000130948
Locus Specific Databases
- Global Variome shared LOVD

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data