VU 0364439
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Catalog number2815-5
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PricePlease ask
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Size5 mg
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Alternative_nameN-[3-Chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
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DescriptionVU-0364439 is a potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor) (EC₅₀ = 19.8 nM in vitro for human mGluR-4).
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CAS Number1246086-78-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₈H₁₃Cl₂N₃O₃S
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Molecular Weight422.29
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~40 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor)
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Storage Condition-20°C
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID46934289
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SMILESC1=CC=C(C(=C1)NS(=O)(=O)C2=C(C=C(C=C2)NC(=O)C3=CC=CC=N3)Cl)Cl
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InChiInChI=1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24)
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InChi KeyIXHCGJXBIHHIEF-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameVU 0364439
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Alternative nameVU 0364439
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