USP34 Core Antibody

  • Catalog number
    6136-50
  • Price
    209.09 USD
  • Size
    50 μg
  • Antibody Target
    USP34 Core
  • Target Alternative Name
    FLJ43910, KIAA0570, KIAA0729, Ubiquitin Specific Protease 34 core domain.
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human
  • Immunogen Sequence
    Recombinant full length protein
  • Accession
    Q70CQ2
  • Gene Id
    9736
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    50 µg of antibody in PBS containing 10% glycerol
  • Purification
    Purified from egg yolk
  • Application
    Western blot
  • Application And Usages
    Western blot: Robust detection of 100 ng of recombinant protein was possible when antibody was used at a final concentration of 5 μg/mL
  • Description
    USP34 Core is a ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. It acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. It recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. It is involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. Its catalytic core consists of residues 1892-2241.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    USP34   Core  
  • Gene symbol
    USP34-DT, USP34
  • Short name
    USP34 Core Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Chicken IgG
  • Alternative name
    USP34 Core (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    USP34 divergent transcript
  • Locus
  • Discovery year
    2020-09-27
  • Entrez gene record
  • Classification
    • Divergent transcripts
Gene info
  • Identity
  • Gene
  • Long gene name
    ubiquitin specific peptidase 34
  • Synonyms gene name
    • ubiquitin specific protease 34
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    2003-09-04
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • Ubiquitin specific peptidases
    • Armadillo like helical domain containing
    • Small nucleolar RNA protein coding host genes
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products
Filters
Contact
Chat with gentaur.com employee