TTP-22
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Catalog numberB2565-5
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PricePlease ask
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Size5 mg
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Alternative_name3-[[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]thio]-propanoic acid, TTP22, TTP 22
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DescriptionTTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these kinases even at 10 μM.
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CAS Number329907-28-0
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₆H₁₄N₂O₂S₂
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Molecular Weight330.4
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Cell PermeableTrue
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Purity≥98% by HPLC
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Solubilities~10 mg/ml in DMSO
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA casein kinase 2 (CK2) inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID1536915
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SMILESCC(C=C1)=CC=C1C2=CSC3=NC=NC(SCCC(O)=O)=C32
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InChiInChI=1S/C16H14N2O2S2/c1-10-2-4-11(5-3-10)12-8-22-16-14(12)15(17-9-18-16)21-7-6-13(19)20/h2-5,8-9H,6-7H2,1H3,(H,19,20)
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InChi KeyRAOULLCLLOGTDA-UHFFFAOYSA-N
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MSDS AvailableTrue
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Gene target
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Gene symbolSNORD114-22, PIRC111, PIRC112, PIRC108, PIRC107, PIRC110, PIRC106, VN1R112P, PIRC109, SNORD116-22
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Short nameTTP-22
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Alternative nameTTP-22
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Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 114-22
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Synonyms
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Locus
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Discovery year2006-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 111
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 112
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 108
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 107
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 110
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 106
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namevomeronasal 1 receptor 112 pseudogene
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Locus
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Discovery year2009-10-06
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Entrez gene record
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RefSeq identity
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Classification
- Vomeronasal receptors
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 109
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 116-22
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box