Trifluorothymidine

• Catalog number
  B1126-50
• Price
  Please ask
• Size
  50 mg

• Alternative_name
  2'-Deoxy-5-trifluoromethyluridine; Triflurdine; TFT
• Description
  Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking viral DNA replication. Decreases CRISPR-mediated HDR (homology-directed repair) efficiency.
• CAS Number
  70-00-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₁₁F₃N₂O₅
• Molecular Weight
  296.2
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>25 mg/ml) of H₂O (>10mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A thymidylate synthase inhibitor and HDR blocker
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00006534
• PubChem CID
  6256
• PubChem CID Link
• SMILES
  C1C(C(OC1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O
• InChi
  InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1
• InChi Key
  VSQQQLOSPVPRAZ-RRKCRQDMSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Trifluorothymidine  
• Short name
  Trifluorothymidine
• Alternative name
  Trifluorothymidine

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