Triciribine

  • Catalog number
    1707-1
  • Price
    Please ask
  • Size
    1 mg
  • Alternative_name
    1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,2,5,6,8-pentaazanaphthylen-3-amine; NSC 154020
  • Description
    Cell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1.
  • CAS Number
    35943-35-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₃H₁₆N₆O₄
  • Molecular Weight
    320.3
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and moisture
  • Tag Line
    An Akt inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD16879015
  • PubChem CID
    65399
  • SMILES
    CN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N
  • InChi
    InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
  • InChi Key
    HOGVTUZUJGHKPL-HTVVRFAVSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Triciribine
  • Alternative name
    Triciribine
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