Triciribine
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Catalog number1707-1
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PricePlease ask
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Size1 mg
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Alternative_name1,5-Dihydro-5-methyl-1-b-D-ribofuranosyl-1,2,5,6,8-pentaazanaphthylen-3-amine; NSC 154020
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DescriptionCell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but does not inhibit Akt kinase activity nor known upstream Akt activators such as PI 3-Kinase and PDK1.
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CAS Number35943-35-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₃H₁₆N₆O₄
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Molecular Weight320.3
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO
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HandlingProtect from air and moisture
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Tag LineAn Akt inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life24 months
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MDL NumberMFCD16879015
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PubChem CID65399
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SMILESCN1C2=NC=NC3=C2C(=CN3C4C(C(C(O4)CO)O)O)C(=N1)N
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InChiInChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1
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InChi KeyHOGVTUZUJGHKPL-HTVVRFAVSA-N
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MSDS AvailableYes
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Gene target
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Short nameTriciribine
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Alternative nameTriciribine
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