Tozasertib (VX-680, MK-0457, VX6)

  • Catalog number
    1595-25
  • Price
    161.17 USD
  • Size
    25 mg
  • Alternative_name
    MK-0457, VX6, VX-681
  • Description
    Tozasertib inhibits Aurora kinases A, B and C with Ki values of 0.6, 18 and 4.6 nM, respectively. It also inhibits Flt-3 and Abl as well as their mutant forms.
  • CAS Number
    639089-54-6
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₃H₂₈N₈OS
  • Molecular Weight
    464.59
  • Cell Permeable
    Yes
  • Purity
    ≥99% by HPLC
  • Solubilities
    DMSO (100 mg/ml)
  • Handling
    Protect from light and moisture
  • Tag Line
    An Aurora kinase inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    RT
  • Shelf Life
    24months
  • MDL Number
    MFCD10565966
  • PubChem CID
    5494449
  • SMILES
    CC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)SC4=CC=C(C=C4)NC(=O)C5CC5
  • InChi
    InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12- 31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H, 3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)
  • InChi Key
    GCIKSSRWRFVXBI-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Gene symbol
    MVK, STYXL1, MDK, MAPKAPK3, EPCAM
  • Short name
    Tozasertib (VX-680, MK-0457, VX6)
  • Alternative name
    Tozasertib (VX-680, MK-0457, VX6)
Gene info
Gene info
Gene info
Gene info
Gene info
Similar products
Filters
Contact
Chat with gentaur.com employee