Thiazovivin

• Catalog number
  1681-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-Benzyl-2-(pyrimidin-4-ylamino)thiazole-4-carboxamide; Tzv
• Description
  Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. Thiazovivin enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB-431542 (Cat. No. 1674) and PD 0325901 (Cat. No.1643).Acts as a Rho-associated Kinase (ROCK) inhibitor. Tzv (2 µM) inhibits ROCK activity and protect hESCs at a similar level as Y-27632 (10 µM) (Cat. No. 1596), a well-known, selective ROCK inhibitor.
• CAS Number
  1226056-71-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₁₃N₅OS
• Molecular Weight
  311.36
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and moisture
• Tag Line
  A hESC survival agent
• Storage Condition
  -20°C
• Shipping Condition
  RT
• Shelf Life
  24 months
• MDL Number
  MFCD16495823
• PubChem CID
  46209426
• PubChem CID Link
• SMILES
  C1=CC=C(C=C1)CNC(=O)C2=CSC(=N2)NC3=NC=NC=C3
• InChi
  InChI=1S/C15H13N5OS/c21-14(17-8-11-4-2-1-3-5-11)12-9-22-15(19-12)20-13- 6-7-16-10-18-13/h1-7,9-10H,8H2,(H,17,21)(H,16,18,19,20)
• InChi Key
  DOBKQCZBPPCLEG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Thiazovivin  
• Short name
  Thiazovivin
• Alternative name
  Thiazovivin

Similar products