T0901317
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Catalog numberB1636-5
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PricePlease ask
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Size5 mg
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Alternative_nameT0901317; T-0901317; T 0901317; N-(2,2,2-trifluoro-ethyl)-N-[4-(2,2,2-tri- fluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide; LXR and FXR agonist
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DescriptionT0901317 is a potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors), with EC50 of ~50 nM and 5 μM, respectively, inhibits nuclear factor/κB (NF/κB).
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CAS Number293754-55-9
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₇H₁₂NSO₃F₉
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Molecular Weight481.33
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors)
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD03412028
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PubChem CID447912
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SMILESC1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
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InChi1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
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InChi KeySGIWFELWJPNFDH-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameT0901317
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Alternative nameT0901317
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