T0901317

  • Catalog number
    B1636-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    T0901317; T-0901317; T 0901317; N-(2,2,2-trifluoro-ethyl)-N-[4-(2,2,2-tri- fluoro-1-hydroxy-1-trifluoromethyl-ethyl)-phenyl]-benzenesulfonamide; LXR and FXR agonist
  • Description
    T0901317 is a potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors), with EC50 of ~50 nM and 5 μM, respectively, inhibits nuclear factor/κB (NF/κB).
  • CAS Number
    293754-55-9
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₁₇H₁₂NSO₃F₉
  • Molecular Weight
    481.33
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors)
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD03412028
  • PubChem CID
    447912
  • SMILES
    C1=CC=C(C=C1)S(=O)(=O)N(CC(F)(F)F)C2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
  • InChi
    1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2
  • InChi Key
    SGIWFELWJPNFDH-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    T0901317
  • Alternative name
    T0901317
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