Superoxide Dismutase 2 (SOD-2) Antibody (2A1)

  • Catalog number
    6169-100
  • Price
    Please ask
  • Size
    100 μl
  • Antibody Target
    SOD2
  • Target Alternative Name
    Superoxide dismutase, mitochondrial, IPOB, MNSOD, MVCD6.
  • Antibody Type
    Monoclonal
  • Clone
    2A1
  • Species Reactivities
    Human, mouse, rat
  • Immunogen Sequence
    Recombinant human protein purified from E.coli
  • Accession
    P04179
  • Gene Id
    6648
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    1 mg/ml
  • Formulation
    100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
  • Purification
    Protein G purified Antibody
  • Application
    Western blot
  • Positive Control
    WB analysis of HeLa cells, HepG2 cells, Mouse brain tissue, Rat Brain tissue lysates
  • Application And Usages
    Western blot: 1 µg/ml.
  • Description
    Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. SOD2 destroys radicals which are normally produced within the cells and which are toxic to biological systems.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Data Sheet Link
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Superoxide   Dismutase   SOD-2   2A1  
  • Gene symbol
    SOD2-OT1, SOD2, SOD3, GCASPC, MIR1289-2, MIR521-2, MIR509-2, MIR512-2, MIR7-2, MIR329-2
  • Short name
    Superoxide Dismutase 2 (SOD-2) Antibody (2A1)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Mouse IgG 1
  • Alternative name
    Superoxide Dismutase 2 (antioxidant enzyme-2) (antibody to-) (2A1)
  • Alternative technique
    antibodies
Gene info
  • Identity
    HGNC:53445
  • Gene
    SOD2-OT1
  • Long gene name
    SOD2 overlapping transcript 1
  • Locus
    6q25.3
  • Discovery year
    2017-04-19
  • Entrez gene record
    100129518
  • RefSeq identity
  • Classification
    • Overlapping transcripts
Gene info
Gene info
  • Identity
    HGNC:11181
  • Gene
    SOD3
  • Long gene name
    superoxide dismutase 3
  • Synonyms gene name
    • superoxide dismutase 3, extracellular
  • Synonyms
  • Locus
    4p15.2
  • Discovery year
    1988-05-08
  • Entrez gene record
    6649
  • Classification
    • Superoxide dismutases
  • VEGA ID
    OTTHUMG00000128565
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Blotting, Western
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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Superoxide Dismutase 2 SOD 2 Antibody 2A1) - Gentaur.com
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