Sulfatinib

  • Catalog number
    B2466-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    HMPL 012; HMPL012; N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide
  • Description
    Sulfatinib is a potent, orally bioavailable and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC₅₀s of in a range of 1 to 24 nM.
  • CAS Number
    1308672-74-3
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₄H₂₈N₆O₃S
  • Molecular Weight
    480.59
  • Cell Permeable
    True
  • Purity
    ≥98% by HPLC
  • Solubilities
    >25 mg/ml in DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A potent VEGFR inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    52920501
  • SMILES
    CC1=CC2=C(N1)C=CC(=C2)OC3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)NCCN(C)C
  • InChi
    InChI=1S/C24H28N6O3S/c1-17-13-19-15-21(7-8-22(19)27-17)33-23-9-10-25-24(29-23)28-20-6-4-5-18(14-20)16-34(31,32)26-11-12-30(2)3/h4-10,13-15,26-27H,11-12,16H2,1-3H3,(H,25,28,29)
  • InChi Key
    TTZSNFLLYPYKIL-UHFFFAOYSA-N
  • MSDS Available
    True
  • Gene target
  • Short name
    Sulfatinib
  • Alternative name
    Sulfatinib
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