Sulfatinib
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Catalog numberB2466-5
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PricePlease ask
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Size5 mg
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Alternative_nameHMPL 012; HMPL012; N-(2-(dimethylamino)ethyl)-1-(3-((4-((2-methyl-1H-indol-5-yl)oxy)pyrimidin-2-yl)amino)phenyl)methanesulfonamide
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DescriptionSulfatinib is a potent, orally bioavailable and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC₅₀s of in a range of 1 to 24 nM.
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CAS Number1308672-74-3
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₄H₂₈N₆O₃S
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Molecular Weight480.59
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Cell PermeableTrue
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Purity≥98% by HPLC
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Solubilities>25 mg/ml in DMSO
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HandlingDo not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag LineA potent VEGFR inhibitor
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life36 months
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PubChem CID52920501
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SMILESCC1=CC2=C(N1)C=CC(=C2)OC3=NC(=NC=C3)NC4=CC=CC(=C4)CS(=O)(=O)NCCN(C)C
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InChiInChI=1S/C24H28N6O3S/c1-17-13-19-15-21(7-8-22(19)27-17)33-23-9-10-25-24(29-23)28-20-6-4-5-18(14-20)16-34(31,32)26-11-12-30(2)3/h4-10,13-15,26-27H,11-12,16H2,1-3H3,(H,25,28,29)
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InChi KeyTTZSNFLLYPYKIL-UHFFFAOYSA-N
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MSDS AvailableTrue
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Gene target
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Short nameSulfatinib
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Alternative nameSulfatinib
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