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Alternative_name
VCRFBI cocktail
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Description
StemBoost™ Reprogramming Cocktail, VCRFBI (100X), is a convenient, sterile-filtered cocktail solution (100X, in DMSO) for the generation of human neuronal cells from adult astrocytes. The cocktail contains the following five small molecules: CHIR99021 (Cat. No. 1677), a GSK-3β inhibitor, 300 μM; RepSox (Cat. No. 1894), a TGFβ inhibitor, 0.1 mM; Forskolin (Cat. No. 1531), a cAMP activator, 1.0 mM; I-BET151 (Cat. No. 2220), a BET bromodomain inhibitor, 200 μM; ISX9 (Cat. No. 2563), a neurogenic differentiation inducer, 1 mM. Also provided separately is a sterile-filtered solution (100X, in DI water) of the HDAC inhibitor Valproic Acid Sodium Salt (Cat. No. 1647), (50 mM).
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CAS Number
See under individual components
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Structure Available
No
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Salt Form
No
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Cell Permeable
True
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Purity
See under individual components
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
A reprogramming cocktail
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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SMILES
N/A
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InChi
N/A
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InChi Key
N/A
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MSDS Available
True
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Additional description
This 1 has passed a sterilization (or sterilization) by filtration or inactivation that has eliminated (removed) or killed (deactivated) all forms of DNA, RNA and enzymes. Also life and other biological agents (such as viruses which some do not consider to be alive but are biological pathogens nonetheless), excluding prions which cannot be killed, including transmissible agents (such as fungi, bacteria, viruses, prions, spore forms, unicellular eukaryotic organisms such as Plasmodium, etc.) present in a specified reagent or on a surface, a volume of fluid, or in a compound such as biological culture medias filtered. Sterilization was achieved with one or more of the following heat, chemicals, irradiation, high pressure, and filtration. Sterilization is distinct from disinfection, sanitization, and pasteurization in that sterilization kills, deactivates, or eliminates all forms of life and other biological agents.