StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)

  • Catalog number
    S246-set
  • Price
    Please ask
  • Size
    10 vials
  • Alternative_name
    VCRFBI cocktail
  • Description
    StemBoost™ Reprogramming Cocktail, VCRFBI (100X), is a convenient, sterile-filtered cocktail solution (100X, in DMSO) for the generation of human neuronal cells from adult astrocytes. The cocktail contains the following five small molecules: CHIR99021 (Cat. No. 1677), a GSK-3β inhibitor, 300 μM; RepSox (Cat. No. 1894), a TGFβ inhibitor, 0.1 mM; Forskolin (Cat. No. 1531), a cAMP activator, 1.0 mM; I-BET151 (Cat. No. 2220), a BET bromodomain inhibitor, 200 μM; ISX9 (Cat. No. 2563), a neurogenic differentiation inducer, 1 mM. Also provided separately is a sterile-filtered solution (100X, in DI water) of the HDAC inhibitor Valproic Acid Sodium Salt (Cat. No. 1647), (50 mM).
  • CAS Number
    See under individual components
  • Structure Available
    No
  • Salt Form
    No
  • Cell Permeable
    True
  • Purity
    See under individual components
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    A reprogramming cocktail
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • SMILES
    N/A
  • InChi
    N/A
  • InChi Key
    N/A
  • MSDS Available
    True
  • Additional description
    This 1 has passed a sterilization (or sterilization) by filtration or inactivation that has eliminated (removed) or killed (deactivated) all forms of DNA, RNA and enzymes. Also life and other biological agents (such as viruses which some do not consider to be alive but are biological pathogens nonetheless), excluding prions which cannot be killed, including transmissible agents (such as fungi, bacteria, viruses, prions, spore forms, unicellular eukaryotic organisms such as Plasmodium, etc.) present in a specified reagent or on a surface, a volume of fluid, or in a compound such as biological culture medias filtered. Sterilization was achieved with one or more of the following heat, chemicals, irradiation, high pressure, and filtration. Sterilization is distinct from disinfection, sanitization, and pasteurization in that sterilization kills, deactivates, or eliminates all forms of life and other biological agents.
  • Gene target
  • Short name
    StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)
  • Technique
    sterile, sterile pure
  • Alternative name
    StemBoost™ Reprogramming Cocktail, VCRFBI, Sterile-Filtered (100X)
  • Alternative technique
    sterilized
MeSH Data
  • Name
  • Concept
    Scope note: A process of separating particulate matter from a fluid, such as air or a liquid, by passing the fluid carrier through a medium that will not pass the particulates. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
  • Tree numbers
    • E05.196.454
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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