Staurosporine
-
Catalog number1048-01
-
PricePlease ask
-
Size100 ug
-
-
Alternative_nameAntibiotic AM-2282
-
DescriptionPotent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site tyrosine. Induces apoptosis in CHO cells at 1 µM.
-
CAS Number62996-74-1
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₂₈H₂₆N₄O₃
-
Molecular Weight466.53
-
Cell PermeableYes
-
Purity>99% by TLC
-
SolubilitiesDMSO ( 25 mg/ml)
-
HandlingProtect from light and moisture
-
Tag LineA protein kinase inhibitor
-
Storage Condition+4°C
-
Shipping ConditionRT
-
Shelf Life12 months
-
MDL NumberMFCD00077402
-
PubChem CID451705
-
SMILESCC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
-
InChiInChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1
-
InChi KeyHKSZLNNOFSGOKW-HMWZOHBLSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameStaurosporine
-
Alternative nameStaurosporine
-