Splitomicin

• Catalog number
  1610-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  1,2-Dihydro-3H-naphtho[2,1-b]pyran-3-one
• Description
  Potent inhibitor of yeast NAD⁺-dependent histone deacetylase Sir2p (IC₅₀ = 60 µM). Sensitizes mammalian cells to a variety of DNA-damaging agents by abrogating Sir2p activity on p53. Acts by either altering or blocking access to the acetylated histone binding pocket.
• CAS Number
  5690-03-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₃H₁₀O₂
• Molecular Weight
  198.2
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (100 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A HDAC inhibitor
• Storage Condition
  +4°C
• Shipping Condition
  RT
• Shelf Life
  24months
• MDL Number
  MFCD08705254
• PubChem CID
  5269
• PubChem CID Link
• SMILES
  C1CC(=O)OC2=C1C3=CC=CC=C3C=C2
• InChi
  InChI=1S/C13H10O2/c14-13-8-6-11-10-4-2-1-3-9(10)5-7-12(11)15-13/h1-5,7H,6,8H2
• InChi Key
  ISFPDBUKMJDAJH-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Splitomicin  
• Short name
  Splitomicin
• Alternative name
  Splitomicin

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