Sildenafil citrate

• Catalog number
  2872-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  1-[[3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-4-methylpiperazine citrate
• Description
  Sildenafil citrate is a potent, orally active phosphodiesterase 5 (PDE5) inhibitor (IC₅₀ = 4 nM). Inhibition of PDE5 enhances the relaxation of smooth muscle in a range of vascular tissues by prolonging the nitric oxide/cGMP-mediated activation of cGMP-dependent protein kinase (PKG). Sildenafil also acts as a vasodilator and this property has been used to control vascular tone in pulmonary arterial hypertension and high-altitude pulmonary edema associated with altitude sickness.
• CAS Number
  171599-83-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₂H₃₀N₆O₄S.C₆H₈O₇
• Molecular Weight
  666.71
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~25 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A potent phosphodiesterase 5 (PDE5) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD09026931
• PubChem CID
  62853
• PubChem CID Link
• SMILES
  CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
• InChi
  InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
• InChi Key
  DEIYFTQMQPDXOT-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Sildenafil   citrate  
• Short name
  Sildenafil citrate
• Alternative name
  Sildenafil citrate

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