SHP099 hydrochloride

• Catalog number
  B1308-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride
• Description
  SHP099 is a potent, and selective, SHP2 inhibitor (IC50 = 0.07 μM) and p-ERK modulation in cells (IC₅₀ = 0.250 μM). SHP099 displays dose-dependent pathway inhibition and antitumor activity in xenograft models.
• CAS Number
  1801747-11-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₂₀Cl₃N₅
• Molecular Weight
  388.72
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, and selective, SHP2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  121241170
• PubChem CID Link
• SMILES
  CC1(CCN(CC1)C2=CN=C(C(=N2)N)C3=C(C(=CC=C3)Cl)Cl)N.Cl
• InChi
  InChI=1S/C16H19Cl2N5.ClH/c1-16(20)5-7-23(8-6-16)12-9-21-14(15(19)22-12)10-3-2-4-11(17)13(10)18;/h2-4,9H,5-8,20H2,1H3,(H2,19,22);1H
• InChi Key
  KHQHYRFUYAXWOQ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SHP099   hydrochloride  
• Short name
  SHP099 hydrochloride
• Alternative name
  SHP099 hydrochloride

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