SC-79

• Catalog number
  2766-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2-Amino-6-chloro-α-cyano-3-(ethoxyca­rbonyl)-4H-1-benzopyran-4-acetic acid ethyl ester
• Description
  SC-79 is an Akt activator. Binds to the pleckstrin homology (PH) domain of Akt preventing membrane translocation but paradoxically activating it in the cytosol. Enhances Akt phosphorylation by upstream protein kinases. Suppresses excitotoxicity-induced neuronal death in vitro and in vivo.
• CAS Number
  305834-79-1
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₇ClN₂O₅
• Molecular Weight
  364.78
• Cell Permeable
  Y
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (~ 100 mg/ml) or EtOH (~ 40 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  An Akt activator
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• SMILES
  ClC1=CC=C(OC(N)=C(C(OCC)=O)C2C(C#N)C(OCC)=O)C2=C1
• InChi
  InChI=1S/C17H17ClN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3
• InChi Key
  DXVKFBGVVRSOLI-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  SC-79  
• Gene symbol
  IGHV3-79, ERMAP, CCDC73, RBMX2, RNU6-79P, SRSF2
• Short name
  SC-79
• Alternative name
  SC-79

Gene info

• Identity
  HGNC:5627
• Gene
  IGHV3-79
• Long gene name
  immunoglobulin heavy variable 3-79 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-79
  • immunoglobulin heavy variable 3-79 pseudogene
• GenBank acession
  • AB019437
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28405
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151871

Gene info

• Identity
  HGNC:15743
• Gene
  ERMAP
• Long gene name
  erythroblast membrane associated protein (Scianna blood group)
• Synonyms gene
  • RD
  • SC
• Synonyms gene name
  • Radin blood group
  • Scianna blood group
  • erythroblast membrane-associated protein
  • erythroblast membrane-associated protein (RD and SC blood groups)
  • erythroblast membrane-associated protein (Scianna blood group)
• Synonyms
  • BTN5
• GenBank acession
  • AF311284
• Locus
  1p34.2
• Discovery year
  2001-09-06
• Entrez gene record
  114625
• Pubmed identfication
  • 11549310
• RefSeq identity
  • NM_018538
• Classification
  • V-set domain containing
  • Butyrophilins
  • Blood group antigens
• VEGA ID
  OTTHUMG00000007619
• Locus Specific Databases
  • Blood Group Antigen Mutation Database
  • LRG_806

Gene info

• Identity
  HGNC:23261
• Gene
  CCDC73
• Long gene name
  coiled-coil domain containing 73
• Synonyms
  • NY-SAR-79
• GenBank acession
  • AK128159
• Locus
  11p13
• Discovery year
  2006-02-11
• Entrez gene record
  493860
• RefSeq identity
  • NM_001008391
• VEGA ID
  OTTHUMG00000166279

Gene info

• Identity
  HGNC:24282
• Gene
  RBMX2
• Long gene name
  RNA binding motif protein X-linked 2
• Synonyms
  • CGI-79
  • Snu17
• GenBank acession
  • AF078865
• Locus
  Xq26.1
• Discovery year
  2004-06-02
• Entrez gene record
  51634
• Pubmed identfication
  • 10810093
• RefSeq identity
  • NM_016024
• Classification
  • RNA binding motif containing
• VEGA ID
  OTTHUMG00000022395

Gene info

• Identity
  HGNC:42569
• Gene
  RNU6-79P
• Long gene name
  RNA, U6 small nuclear 79, pseudogene
• Synonyms gene
  • RNU6-79
• Synonyms gene name
  • RNA, U6 small nuclear 79
• Locus
  13q22.1
• Discovery year
  2011-08-08
• Entrez gene record
  100873779
• RefSeq identity
  • NR_046945

Gene info

• Identity
  HGNC:10783
• Gene
  SRSF2
• Long gene name
  serine and arginine rich splicing factor 2
• Synonyms gene
  • SFRS2
• Synonyms gene name
  • splicing factor, arginine/serine-rich 2
  • serine/arginine-rich splicing factor 2
• Synonyms
  • SC-35
  • SC35
  • PR264
  • SFRS2A
• Synonyms name
  • SR splicing factor 2
• GenBank acession
  • M90104
• Locus
  17q25.2
• Discovery year
  1993-09-17
• Entrez gene record
  6427
• Pubmed identfication
  • 8530103
  • 20516191
• RefSeq identity
  • NM_003016
• Classification
  • Serine and arginine rich splicing factors
  • RNA binding motif containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000177547
• Locus Specific Databases
  • LRG_640

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