SB 939

• Catalog number
  2285-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  3-​[2-​butyl-​1-​[2-​(diethylamino)ethyl]-​1H-​benzimidazol-​5-​yl]-​N-​hydroxy-​2E-​propenamide; Pracinostat
• Description
  An orally available pan-histone deacetylase (HDAC) inhibitor binding all HDAC isozymes with similar affinity (Kis = 16-28 nM) with the exception of HDAC6 and 7 (Kis = 247 and 104 nM, respectively). SB 939 demonstrates good bioavailability in vivo and significantly inhibits tumor growth in various xenograft mouse models at doses ranging from 25-100 mg/kg.
• CAS Number
  929016-96-6
• Structure Available
  Yes
• Peptide sequence
  No
• Salt Form
  No
• Molecular Formula
  C₂₀H₃₀N₄O₂
• Molecular Weight
  358.48
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO
• Handling
  Protect from light and moisture
• Tag Line
  A pan-HDAC inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  49855250
• PubChem CID Link
• SMILES
  CCCCC1=NC2=C(N1CCN(CC)CC)C=CC(=C2)C=CC(=O)NO
• InChi
  InChI=1S/C20H30N4O2/c1-4-7-8-19-21-17-15-16(10-12-20(25)22-26)9-11-18(17)24(19)14-13-23(5-2)6-3/h9-12,15,26H,4-8,13-14H2,1-3H3,(H,22,25)/b12-10+
• InChi Key
  JHDKZFFAIZKUCU-ZRDIBKRKSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  939  
• Short name
  SB 939
• Alternative name
  SB 939

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