Salermide

• Catalog number
  1873-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  N-​[3-​[[(2-​hydroxy-​1-​naphthalenyl)methylene]amino]phenyl]-​a-​methyl-​benzeneacetamide
• Description
  Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through reactivation of proapoptotic genes epigenetically repressed exclusively in cancer cells by SIRT1.
• CAS Number
  1105698-15-4
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₂₂N₂O₂
• Molecular Weight
  394.47
• Cell Permeable
  Yes
• Purity
  ≥98%
• Solubilities
  DMSO (100 mM)
• Handling
  Protect from air and moisture
• Tag Line
  A SIRT1 and SIRT2 inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• MDL Number
  MFCD12912446
• PubChem CID
  42626405
• PubChem CID Link
• SMILES
  CC(C1=CC=CC=C1)C(=O)NC2=CC=CC(=C2)NC=C3C(=O)C=CC4=CC=CC=C43
• InChi
  InChI=1S/C26H22N2O2/c1-18(19-8-3-2-4-9-19)26(30)28-22-12-7-11-21(16-22) 27-17-24-23-13-6-5-10-20(23)14-15-25(24)29/h2-18,27H,1H3,(H,28, 30)/b24-17-
• InChi Key
  UADRPWLRVLBVBC-ULJHMMPZSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Salermide  
• Short name
  Salermide
• Alternative name
  Salermide

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