Rogaratinib

Alternative_name

BAY 1163877; 4-((4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)methyl)piperazin-2-one; BAY1163877; BAY-1163877
Description

Rogaratinib (BAY-1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor.
CAS Number

1443530-05-9
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₃H₂₆N₆O₃S
Molecular Weight

466.56
Cell Permeable

True
Purity

≥98% by HPLC
Solubilities

>5 mg/ml in DMSO
Handling

Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Tag Line

A potent and selective fibroblast growth factor receptor (FGFR) inhibitor
Storage Condition

-20ºC
Shipping Condition

Gel Pack
Shelf Life

36 months
PubChem CID

71611869
PubChem CID Link
SMILES

CC1=CC2=C(C(=C1)OC)SC(=C2)C3=C4C(=NC=NN4C(=C3COC)CN5CCNC(=O)C5)N
InChi

InChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8,12H,4-5,9-11H2,1-3H3,(H,25,30)(H2,24,26,27)
InChi Key

HNLRRJSKGXOYNO-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

True