RIP Antibody

• Catalog number
  3279-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  RIP
• Target Alternative Name
  RIPK1, FLJ39204, Rinp, RIPK1, Receptor interacting protein
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 645 of human RIP
• Accession
  Q13546
• Gene Id
  8737
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit anti-RIP polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot, Immunoprecipitation, Immunohistochemistry
• Application And Usages
  Western blot analysis (2-6 µg/ml), immunoprecipitation and Immunohistochemistry. However, the optimal conditions should be determined individually.
• Description
  RIP (Receptor Interacting Protein) is a 74 kDa Ser/Thr kinase which interacts with CD95 (Fas/Apo1) receptor and the tumor necrosis factor receptor (TNFR1). It is a cell death domain adapter protein which can bind to the adapter proteins TRADD, RAID, and TRAF2. RIP contains an N-terminal region with homology to protein kinase, an intermediate domain capable of association with MAPKKK and a C-terminal region containing an intracellular death domain motif. RIP activates both p38 MAP kinase and SAPK families. In vitro, RIP induces apoptosis, as well as SAPK/JNK and NF-kB activation. RIP possesses kinase activity as it autophosphorylates itself on serine and threonine residues.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RIP  
• Gene symbol
  RIPK1, AGFG1, RPAIN, KRR1, RALBP1, MPRIP
• Short name
  RIP Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  RIP (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:10019
• Gene
  RIPK1
• Long gene name
  receptor interacting serine/threonine kinase 1
• Synonyms gene name
  • receptor (TNFRSF)-interacting serine-threonine kinase 1
• Synonyms
  • RIP
• Synonyms name
  • receptor-interacting protein kinase 1
• GenBank acession
  • U25994
• Locus
  6p25.2
• Discovery year
  1999-05-07
• Entrez gene record
  8737
• Pubmed identfication
  • 7538908
  • 8612133
• RefSeq identity
  • NM_003804
• Classification
  • Ripoptosome
• VEGA ID
  OTTHUMG00000014134

Gene info

• Identity
  HGNC:5175
• Gene
  AGFG1
• Long gene name
  ArfGAP with FG repeats 1
• Synonyms gene
  • HRB
• Synonyms gene name
  • HIV-1 Rev binding protein
• Synonyms
  • RIP
  • RAB
• Locus
  2q36.3
• Discovery year
  1996-11-15
• Entrez gene record
  3267
• Pubmed identfication
  • 7637788
• RefSeq identity
  • NM_004504
• Classification
  • ArfGAPs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133186

Gene info

• Identity
  HGNC:28641
• Gene
  RPAIN
• Long gene name
  RPA interacting protein
• Synonyms
  • MGC4189
  • RIP
  • hRIP
• GenBank acession
  • AY775314
• Locus
  17p13.2
• Discovery year
  2006-05-08
• Entrez gene record
  84268
• Pubmed identfication
  • 16135809
  • 16008515
• RefSeq identity
  • NM_001033002
• VEGA ID
  OTTHUMG00000177872

Gene info

• Identity
  HGNC:5176
• Gene
  KRR1
• Long gene name
  KRR1 small subunit processome component homolog
• Synonyms gene
  • HRB2
• Synonyms gene name
  • HIV-1 rev binding protein 2
  • KRR1, small subunit (SSU) processome component, homolog (yeast)
  • KRR1, small subunit processome component homolog
• Synonyms
  • RIP-1
• GenBank acession
  • U55766
• Locus
  12q21.2
• Discovery year
  1999-12-09
• Entrez gene record
  11103
• Pubmed identfication
  • 7505766
  • 11027267
  • 11359931
  • 8675026
• RefSeq identity
  • NM_007043
• Classification
  • SSU processome
• VEGA ID
  OTTHUMG00000169759

Gene info

• Identity
  HGNC:9841
• Gene
  RALBP1
• Long gene name
  ralA binding protein 1
• Synonyms
  • RLIP76
  • RIP1
  • RIP
• GenBank acession
  • L42542
• Locus
  18p11.22
• Discovery year
  2000-02-11
• Entrez gene record
  10928
• Pubmed identfication
  • 7673236
• RefSeq identity
  • NM_006788
• VEGA ID
  OTTHUMG00000131596

Gene info

• Identity
  HGNC:30321
• Gene
  MPRIP
• Long gene name
  myosin phosphatase Rho interacting protein
• Synonyms
  • RHOIP3
  • M-RIP
  • p116Rip
• Synonyms name
  • Rho interacting protein 3
• GenBank acession
  • BC014102
• Locus
  17p11.2
• Discovery year
  2008-06-02
• Entrez gene record
  23164
• Pubmed identfication
  • 10048485
• RefSeq identity
  • NM_015134
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000059276

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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