RhoGDI Antibody

• Catalog number
  A1161-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  ARHGDIA
• Target Alternative Name
  GDIA1, Rho GDP-dissociation inhibitor 1, Rho GDI 1, Rho-GDI
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RhoGDI alpha
• Accession
  P52565
• Gene Id
  396
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IH
• Positive Control
  WB:A549, DLD, HepG2 cell lysates; IHC: human breast cancer tissue
• Application And Usages
  WB; 1:500 – 1:2000, IHC; 1:50 – 1:200
• Description
  Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  RhoGDI  
• Gene symbol
  ARHGDIG, ARHGDIA
• Short name
  RhoGDI Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  RhoGDI (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:680
• Gene
  ARHGDIG
• Long gene name
  Rho GDP dissociation inhibitor gamma
• Synonyms gene name
  • Rho GDP dissociation inhibitor (GDI) gamma
• Synonyms
  • RHOGDI-3
• Synonyms name
  • RhoGDI gamma
• GenBank acession
  • U82532
• Locus
  16p13.3
• Discovery year
  1997-07-11
• Entrez gene record
  398
• Pubmed identfication
  • 9113980
  • 11967128
• VEGA ID
  OTTHUMG00000064892

Gene info

• Identity
  HGNC:678
• Gene
  ARHGDIA
• Long gene name
  Rho GDP dissociation inhibitor alpha
• Synonyms gene
  • GDIA1
• Synonyms gene name
  • Rho GDP dissociation inhibitor (GDI) alpha
• Synonyms
  • RHOGDI
• GenBank acession
  • BC028333
• Locus
  17q25.3
• Discovery year
  1996-04-30
• Entrez gene record
  396
• Pubmed identfication
  • 9186513
• RefSeq identity
  • NM_004309
• VEGA ID
  OTTHUMG00000178352

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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