Rhein

• Catalog number
  B2737-250
• Price
  Please ask
• Size
  250 mg

• Alternative_name
  9,10-dihydro-4,5-dihydroxy-9,10-dioxo-2-anthracenecarboxylic acid,NSC-38629
• Description
  Rhein is an anthraquinone derivative that displays diverse biological activities, including anticancer, antioxidant, and anti-inflammatory activities. Also acts as a Fat mass and obesity-associated protein FTO (mRNA N6-methyladenine demethylase) inhibitor (IC50 = 1.2 - 21 μM; Ki = 1.8 μM). Also inhibits ALKBH3 and ALKBH2 (IC50 values are 5.3 and 9.1 μM, respectively). Sensitizes glioblastoma cells to alkylating agents.
• CAS Number
  478-43-3
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₅H₈O₆
• Molecular Weight
  284.22
• Cell Permeable
  1
• Purity
  ≥95%
• Solubilities
  ~10 mg/ml DMSO
• Handling
  Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• PubChem CID
  10168
• PubChem CID Link
• SMILES
  C1=CC2=C(C(=C1)O)C(=O)C3=C(C2=O)C=C(C=C3O)C(=O)O
• InChi
  InChI=1S/C15H8O6/c16-9-3-1-2-7-11(9)14(19)12-8(13(7)18)4-6(15(20)21)5-10(12)17/h1-5,16-17H,(H,20,21)
• InChi Key
  FCDLCPWAQCPTKC-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  1

• Gene target
  Rhein  
• Short name
  Rhein
• Alternative name
  Rhein

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