RG 108

• Catalog number
  1679-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  N-Phthalyl-L-tryptophan
• Description
  A DNA methyltransferase (DNMT) inhibitor. RG108 causes demethylation and reactivation of tumor suppressor genes, but it does not affect the methylation of centromeric satellite sequences. In combination with BIX 01294 (Cat. No. 1678-5), RG 108 enhances reprogramming.
• CAS Number
  48208-26-0
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₄N₂O₄
• Molecular Weight
  334.33
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (10 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A DNA methyltransferase (DNMT) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  24 months
• PubChem CID
  702558
• PubChem CID Link
• SMILES
  C1=CC=C2C(=C1)C(=O)N(C2=O)C(CC3=CNC4=CC=CC=C43)C(=O)O
• InChi
  InChI=1S/C19H14N2O4/c22-17-13-6-1-2-7-14(13)18(23)21(17)16(19(24)25)9-11-10-20-15-8-4-3-5-12(11)15/h1-8,10,16,20H,9H2,(H,24,25)/t16-/m0/s1
• InChi Key
  HPTXLHAHLXOAKV-INIZCTEOSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  108  
• Short name
  RG 108
• Alternative name
  RG 108

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