Reserpine

  • Catalog number
    B2681-10
  • Price
    Please ask
  • Size
    10 mg
  • Alternative_name
    NSC 59272,NSC 237659,(3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester,Rausedil
  • Description
    Reserpine is an alkaloid isolated from dried roots of R. serpentine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectively). It also inhibits adrenaline induced-cutaneous blood vessel constriction and diminishes the effect of hyperthyroidism on cardiovascular and nervous system. Reserpine also inhibits the multidrug resistance protein P-glycoprotein (IC₅₀ = 0.5 µM).
  • CAS Number
    50-55-5
  • Structure Available
    1
  • Molecular Formula
    C₃₃H₄₀N₂O₉
  • Molecular Weight
    608.68
  • Cell Permeable
    1
  • Purity
    ≥98% by HPLC
  • Solubilities
    ~10 mg/ml DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    Vesicular monoamine transporter inhibitor
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00005091
  • PubChem CID
    5770
  • SMILES
    COC1C(CC2CN3CCC4=C(C3CC2C1C(=O)OC)NC5=C4C=CC(=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC
  • InChi
    InChI=1S/C33H40N2O9/c1-38-19-7-8-20-21-9-10-35-16-18-13-27(44-32(36)17-11-25(39-2)30(41-4)26(12-17)40-3)31(42-5)28(33(37)43-6)22(18)15-24(35)29(21)34-23(20)14-19/h7-8,11-12,14,18,22,24,27-28,31,34H,9-10,13,15-16H2,1-6H3/t18-,22+,24-,27-,28+,31+/m1/s1
  • InChi Key
    QEVHRUUCFGRFIF-MDEJGZGSSA-N
  • MSDS Available
    1
  • Gene target
  • Short name
    Reserpine
  • Alternative name
    Reserpine
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