Radotinib

• Catalog number
  9613-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-(pyrazin-2-yl)pyrimidin-2-yl)amino)benzamide; IY-5511
• Description
  Radotinib is a BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI). Also inhibits PDGFR thereby blocking PDGFR-mediated signal transduction pathways. Displays antineoplastic activities.
• CAS Number
  926037-48-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₇H₂₁F₃N₈O
• Molecular Weight
  530.5
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A BCR-ABL1-specific second-generation tyrosine kinase inhibitor (TKI)
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  16063245
• PubChem CID Link
• SMILES
  CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5
• InChi
  InChI=1S/C27H21F3N8O/c1-16-3-4-18(9-23(16)37-26-33-6-5-22(36-26)24-13-31-7-8-32-24)25(39)35-20-10-19(27(28,29)30)11-21(12-20)38-14-17(2)34-15-38/h3-15H,1-2H3,(H,35,39)(H,33,36,37)
• InChi Key
  DUPWHXBITIZIKZ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Radotinib  
• Short name
  Radotinib
• Alternative name
  Radotinib

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