Rad17 Antibody

• Catalog number
  3484R-30T
• Price
  Please ask
• Size
  30 µg

• Antibody Target
  Rad17
• Target Alternative Name
  CCYC, R24L, RAD24, HRAD17, RAD17SP, FLJ41520, RAD17
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 645 of human Rad17
• Accession
  O75943
• Gene Id
  5884
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  30 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the mature forms of Rad17 (~55 kDa and ~45 kDa) of human, mouse and rat origins. Reactivity to other species has not been tested.
• Description
  Rad17 is an essential component of cell cycle checkpoints activated by DNA damage and disruption of DNA replication. DNA lesions such as single- and double-strand breaks, inter- and intra-strand cross-links, and base modifications hamper transcription and replication, resulting in cell cycle arrest, apoptosis, and mutagenesis. Phosphorylation of Rad17 at Ser635 and Ser645 is a critical early event during checkpoint signaling in DNA damaged cells.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Rad17  
• Gene symbol
  RAD17P1, RAD17, RAD17P2
• Short name
  Rad17 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Rad17 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9808
• Gene
  RAD17P1
• Long gene name
  RAD17 pseudogene 1
• Synonyms gene name
  • RAD17 (S. pombe) homolog, pseudogene 1
  • RAD17 homolog (S. pombe) pseudogene 1
• Synonyms
  • HRAD17P1
• GenBank acession
  • AJ131309
• Locus
  7p21.1
• Discovery year
  1999-02-15
• Entrez gene record
  9207
• VEGA ID
  OTTHUMG00000152462

Gene info

• Identity
  HGNC:9807
• Gene
  RAD17
• Long gene name
  RAD17 checkpoint clamp loader component
• Synonyms gene name
  • RAD1 (S. pombe) homolog
  • RAD17 homolog (S. pombe)
• Synonyms
  • Rad24
  • RAD17Sp
  • CCYC
• GenBank acession
  • AF085736
• Locus
  5q13.2
• Discovery year
  1998-07-31
• Entrez gene record
  5884
• Pubmed identfication
  • 9869296
  • 9660800
• RefSeq identity
  • NM_133344
• VEGA ID
  OTTHUMG00000099357

Gene info

• Identity
  HGNC:9809
• Gene
  RAD17P2
• Long gene name
  RAD17 pseudogene 2
• Synonyms gene name
  • RAD17 (S. pombe) homolog, pseudogene 2
  • RAD17 homolog (S. pombe) pseudogene 2
• Synonyms
  • HRAD17P2
• GenBank acession
  • AJ131310
• Locus
  13q14.2
• Discovery year
  1999-02-15
• Entrez gene record
  9206
• Pubmed identfication
  • 9660800
• VEGA ID
  OTTHUMG00000016908

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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