Plasmin Activity Assay Kit (Colorimetric)

• Catalog number
  K945-100
• Price
  Please ask
• Size
  100 assays

• Description
  to detect plasmin activity in samples
• Summary
  BioVision’s Plasmin Activity Assay Kit utilizes the ability of active plasmin to hydrolyze the synthetic substrate thereby releasing pNA (chromophore), which can be easily quantified at OD 405 nm. The stable colorimetric signal is directly proportional to the plasmin activity in samples. The kit includes a specific inhibitor that can be used to compensate for the potential non-specific background in unknown samples. Our assay kit is simple, specific and can detect as low as 40 µU of plasmin activity in samples.
• Detection Method
  Absorbance, OD 405 nm
• Species Reactivity
  All
• Applications
  Measurement of Plasmin activity in Biological Samples: e.g. Plasma, Analysis and study of Fibrinolytic system
• Sample Type
  Biological Fluids: Plasma, etc.
• Features Benefits
  Specific, Can detect as low as 40 µU of plasmin activity in samples, Simple
• Storage Conditions
  -20°C
• Shipping Conditions
  Gel Pack
• Shelf life
  12 months
• Background
  Plasmin (EC 3.4.21.7) is a serine protease that is mainly present in plasma. It plays a key role in the degradation of fibrin clots in the blood and extracellular matrix protein components. Plasmin is involved in various physiological and pathological processes, including fibrinolysis, thrombolysis, wound healing and cancer progression. Malignant cells have been shown to enhance the generation of plasmin that can modify the tumor microenvironment and contribute to cell invasion. High concentrations of plasmin may lead to fibrinolysis and uncontrollable bleeding, while deficiency of plasmin may lead to thrombus that causes myocardial infarction and stroke. The proteolytic activity of plasmin is tightly regulated either by the activation of its precursor, plasminogen or its inhibition by the endogenous plasmin inhibitors such as plasminogen activator inhibitor-1 or α2-Antiplasmin. BioVision’s Plasmin Activity Assay Kit utilizes the ability of active plasmin to hydrolyze the synthetic substrate thereby releasing pNA (chromophore), which can be easily quantified at OD 405 nm. The stable colorimetric signal is directly proportional to the plasmin activity in samples. The kit includes a specific inhibitor that can be used to compensate for the potential non-specific background in unknown samples. Our assay kit is simple, specific and can detect as low as 40 µU of plasmin activity in samples.
• Data Sheet Link
• Test
  Biovision supplies other types of Assays as 1.
• Properties
  Colorimetric assays or detection use UV absorption or enzymatic color reaction.

• Gene target
  Plasmin   Activity   Kit  
• Short name
  Plasmin Activity Assay Kit (Colorimetric)
• Technique
  colorimetric, Assay, assays, colorimetry
• Host
  Assay
• Alternative name
  Plasmin Activity test reagent (colorimetry)
• Alternative technique
  assays, arrays, kits
• Alternative to gene target
  v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, C-Kit and CD117 and PBT and SCFR, KIT and IDBG-18980 and ENSG00000157404 and 3815, transferase activity, Extracellular, Kit and IDBG-172083 and ENSMUSG00000005672 and 16590, KIT and IDBG-642326 and ENSBTAG00000002699 and 280832

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