PKC gamma, Active

Synonyms

PKC, protein kinase C, gammaprotein kinase C
Alternative_names

PKC, protein kinase C, gammaprotein kinase C
Description

Phosphorylate a wide variety of protein targets
Recombinant

Yes
Source

Baculovirus (Sf9 insect cells)
Purity by SDS PAGE

≥80%
Assay

SDS-PAGE
Activity Specifications test method

The specific activity of PKCγ was determined to be 512 nmol /min/mg as per activity assay protocol.
Molecular Weight

105.0 kDa
Storage Temp

-80°C
Shipping

dry ice
Shelf Life

12 months
Concentration

0.1mg/ml
Appearance

Liquid
Physical form description

Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Background Information

PKCγ is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can phosphorylate a wide variety of protein targets known to be involved in diverse cellular signaling pathways. In the brain, PKC is translocated to cell membranes during ischemia and is rapidly removed or degraded during the second otherwise lethal ischemic insult in preconditioned brains. This suggest that ischemic preconditioning enhances downregulation of cell signaling mediated by PKC and may thereby provide neuroprotection (1).
Handling

Centrifuge the vial prior to opening.
Usage

For Research Use Only! Not to be used in humans
Datasheet

Identity

HGNC:30500
Gene

PRRT2
Long gene name

proline rich transmembrane protein 2
Synonyms gene
- ICCA
- DYT10
Synonyms gene name
- infantile convulsions and paroxysmal choreoathetosis
- dystonia 10
- proline-rich transmembrane protein 2
Synonyms
- FLJ25513
- DKFZp547J199
- IFITMD1
- FICCA
- DSPB3
- PKC
- EKD1
Synonyms name
- interferon induced transmembrane protein domain containing 1
- dispanin subfamily B member 3
GenBank acession
- BC011405
Locus

16p11.2
Discovery year

2005-11-25
Entrez gene record

112476
Pubmed identfication
RefSeq identity
- NM_145239
Classification
- interferon induced transmembrane protein domain containing
VEGA ID

OTTHUMG00000177142