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Alternative_name
(8S,10S)-10-(((2R,4S,5S,6S)-4-amino-6-methyl-5-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
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Description
Pirarubicin is an analog of doxorubicin, that acts as an antineoplastic drug. Pirarubicin is transported into cells via a sodium-dependent nucleoside transporter. It is used to intercalate DNA and inhibit the activity of topoisomerase II and induce DNA crosslinking.
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CAS Number
72496-41-4
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₃H₃₇NO₁₂
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Molecular Weight
627.64
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
EtOH (~25 mg/ml)
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Handling
Protect from air and light
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Tag Line
An anticancer drug
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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MDL Number
MFCD00869742
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PubChem CID
636397
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SMILES
CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6
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InChi
InChI=1S/C32H37NO12/c1-14-31(45-21-8-3-4-9-42-21)17(33)10-22(43-14)44-19-12-32(40,20(35)13-34)11-16-24(19)30(39)26-25(28(16)37)27(36)15-6-5-7-18(41-2)23(15)29(26)38/h5-7,14,17,19,21-22,31,34,37,39-40H,3-4,8-13,33H2,1-2H3/t14-,17-,19-,21-,22-,31+,32-/m0/s1
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InChi Key
KMSKQZKKOZQFFG-HSUXVGOQSA-N
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MSDS Available
Yes