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Alternative_name
(2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane,NSC-619043
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Description
Phyllanthin is a major bioactive lignan found in many Phyllanthus species. It displays various biochemical and pharmacological properties especially on its hepatoprotective effects. It scavenges DPPH radicals with an IC50 value of 7.4 µM and, at 30 µM, has been shown to alleviate carbon tetrachloride-induced lipid peroxidation and cytotoxicity in a human hepatoma HepG2 cell line.
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CAS Number
10351-88-9
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₄H₃₄O₆
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Molecular Weight
418.52
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Cell Permeable
1
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Purity
≥98%
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Solubilities
~10 mg/ml DMSO
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
A major bioactive lignan found in many Phyllanthus species
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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MDL Number
MFCD17166965
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PubChem CID
358901
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SMILES
COC1=C(OC)C=C(C[C@]([C@@](CC2=CC=C(OC)C(OC)=C2)([H])COC)([H])COC)C=C1
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InChi
InChI=1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1 Computed by InChI 1.0.5 (PubChem release 2019.06.18)
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InChi Key
KFLQGJQSLUYUBF-WOJBJXKFSA-N
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MSDS Available
1