Phospho SMAD3 (Ser425) Antibody

• Catalog number
  A1987-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  Phospho SMAD3 (Ser425)
• Target Alternative Name
  MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3
• Antibody Type
  Polyclonal
• Species Reactivities
  Chicken, Human
• Immunogen Sequence
  KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human SMAD3
• Accession
  P84022
• Gene Id
  4088
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  Immunohistochemistry (IHC), Western Blotting
• Application And Usages
  WB 1:500 - 1:1000, IHC 1:100 - 1:200
• Description
  The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3.
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  True
• Immunocytochemistry Verified
  True
• Immunofluorescence Verified
  False
• Immunoprecipitation Verified
  False
• FACS Verified
  False
• ELISA Verified
  False
• ChIP Verified
  False
• Dot Blot Verified
  False
• Flow Cytometry Verified
  False
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho   SMAD3   Ser425  
• Gene symbol
  SMAD3
• Short name
  Phospho SMAD3 (Ser425) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  IgG
• Alternative name
  phosphorilated SMAD family member 3 (Ser425) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  SMAD family member 3, HSPC193 and HsT17436 and JV15-2 and LDS1C and LDS3 and MADH3, SMAD3 and IDBG-18366 and ENSG00000166949 and 4088, transforming growth factor beta receptor, nuclei, Smad3 and IDBG-175693 and ENSMUSG00000032402 and 17127, SMAD3 and IDBG-645466 and ENSBTAG00000012599 and 515125

Gene info

• Identity
  HGNC:6769
• Gene
  SMAD3
• Long gene name
  SMAD family member 3
• Synonyms gene
  • MADH3
• Synonyms gene name
  • MAD, mothers against decapentaplegic homolog 3 (Drosophila)
  • SMAD, mothers against DPP homolog 3 (Drosophila)
• Synonyms
  • JV15-2
  • HsT17436
• GenBank acession
  • BC050743
• Locus
  15q22.33
• Discovery year
  1996-11-15
• Entrez gene record
  4088
• Pubmed identfication
  • 8774881
  • 8673135
• RefSeq identity
  • NM_005902
• Classification
  • SMAD family
• VEGA ID
  OTTHUMG00000133230
• Locus Specific Databases
  • The Globin Gene Server

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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