Phospho PFKFB2 (Ser483) Antibody

  • Catalog number
    A1958-100
  • Price
    Please ask
  • Size
    100 µl
  • Antibody Target
    Phospho PFKFB2 (Ser483)
  • Target Alternative Name
    6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Bovine, Rat, Mouse, Human
  • Immunogen Sequence
    KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PFKFB2.
  • Accession
    O60825
  • Gene Id
    5208
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
  • Purification
    Affinity purified
  • Application
    Western Blotting
  • Application And Usages
    WB 1:500 - 1:1000
  • Description
    The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    True
  • Immunocytochemistry Verified
    False
  • Immunofluorescence Verified
    False
  • Immunoprecipitation Verified
    False
  • FACS Verified
    False
  • ELISA Verified
    False
  • ChIP Verified
    False
  • Dot Blot Verified
    False
  • Flow Cytometry Verified
    False
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    Phospho   PFKFB2   Ser483  
  • Gene symbol
    PFKFB2
  • Short name
    Phospho PFKFB2 (Ser483) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    IgG
  • Alternative name
    phosphorilated PFKFB2 (Ser483) (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • Locus
  • Discovery year
    1991-05-09
  • Entrez gene record
  • Classification
    • 6-phosphofructo-2-kinases/fructose-2,6-biphosphatases
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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