Phospho PFKFB2 (Ser483) Antibody
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Catalog number
A1958-100
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Price
Please ask
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Size
100 µl
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Antibody Target
Phospho PFKFB2 (Ser483)
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Target Alternative Name
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2; 6PF-2-K/Fru-2,6-P2ase 2; PFK/FBPase 2; 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
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Antibody Type
Polyclonal
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Species Reactivities
Bovine, Rat, Mouse, Human
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Immunogen Sequence
KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PFKFB2.
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Accession
O60825
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Gene Id
5208
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
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Purification
Affinity purified
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Application
Western Blotting
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Application And Usages
WB 1:500 - 1:1000
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Description
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene.
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
True
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Immunocytochemistry Verified
False
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Immunofluorescence Verified
False
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Immunoprecipitation Verified
False
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FACS Verified
False
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ELISA Verified
False
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ChIP Verified
False
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Dot Blot Verified
False
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Flow Cytometry Verified
False
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
PFKFB2
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Short name
Phospho PFKFB2 (Ser483) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
IgG
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Alternative name
phosphorilated PFKFB2 (Ser483) (antibody to-)
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Alternative technique
antibodies
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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