Phospho PAK4 (Ser474) Antibody

• Catalog number
  A1973-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  Phospho PAK2 (Ser474)
• Target Alternative Name
  KIAA1142; Serine/threonine-protein kinase PAK 4; p21-activated kinase 4; PAK-4
• Antibody Type
  Polyclonal
• Species Reactivities
  Bovine, Rat, Mouse, Human
• Immunogen Sequence
  KLH-conjugated synthetic peptide targeting a sequence within the C-term region of human PAK4.
• Accession
  O96013
• Gene Id
  10298
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  Immunofluorescence (IF), Western Blotting
• Application And Usages
  WB 1:500 - 1:1000, IF 1:100 - 1:500
• Description
  PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Storage Condition
  -20ºC
• Shipping Condition
  Gel Pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  True
• Immunocytochemistry Verified
  False
• Immunofluorescence Verified
  True
• Immunoprecipitation Verified
  False
• FACS Verified
  False
• ELISA Verified
  False
• ChIP Verified
  False
• Dot Blot Verified
  False
• Flow Cytometry Verified
  False
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho   PAK4   Ser474  
• Gene symbol
  PAK4
• Short name
  Phospho PAK4 (Ser474) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  IgG
• Alternative name
  phosphorilated PAK4 (Ser474) (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16059
• Gene
  PAK4
• Long gene name
  p21 (RAC1) activated kinase 4
• Synonyms gene name
  • p21(CDKN1A)-activated kinase 4
  • p21 protein (Cdc42/Rac)-activated kinase 4
• GenBank acession
  • AJ011855
• Locus
  19q13.2
• Discovery year
  2001-07-12
• Entrez gene record
  10298
• Pubmed identfication
  • 9822598
  • 10461188
• VEGA ID
  OTTHUMG00000182800

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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