Phospho HDAC5 (Ser498) Antibody
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Catalog number
A1955-100
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Price
Please ask
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Size
100 µl
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Antibody Target
Phospho HDAC5 (Ser498)
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Target Alternative Name
KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9
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Antibody Type
Polyclonal
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Species Reactivities
Bovine, Porcine, Rat, Mouse, Human
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Immunogen Sequence
KLH-conjugated synthetic peptide targeting a sequence within the center region of human HDAC5.
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Accession
Q9UQL6
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Gene Id
10014
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Appearance
Colorless liquid
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Form
Liquid
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Formulation
In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide
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Purification
Affinity purified
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Application
Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blotting
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Application And Usages
WB 1:500 - 1:1000, IHC 1:100 - 1:200, IF 1:100 - 1:500
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Description
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene.
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
12 months
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Usage
For Research Use Only! Not to be used in humans.
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Handling
The antibody solution should be gently mixed before use.
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Western Blot Verified
True
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Immunocytochemistry Verified
True
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Immunofluorescence Verified
True
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Immunoprecipitation Verified
False
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FACS Verified
False
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ELISA Verified
False
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ChIP Verified
False
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Dot Blot Verified
False
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Flow Cytometry Verified
False
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Properties
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
HDAC5
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Short name
Phospho HDAC5 (Ser498) Antibody
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
IgG
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Alternative name
phosphorilated histone deacetylase 5 (Ser498) (antibody to-)
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Alternative technique
antibodies
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Alternative to gene target
histone deacetylase 5, HD5 and NY-CO-9, HDAC5 and IDBG-53295 and ENSG00000108840 and 10014, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac5 and IDBG-212520 and ENSMUSG00000008855 and 15184, HDAC5 and IDBG-640847 and ENSBTAG00000016254 and 504242
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Gene info
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Identity
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Gene
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Long gene name
histone deacetylase 5
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Synonyms
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GenBank acession
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Locus
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Discovery year
2000-11-28
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histone deacetylases, class IIA
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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