Phospho-Connexin 43 (Ser368) Antibody

  • Catalog number
    A1268-100
  • Price
    Please ask
  • Size
    100 µl
  • Antibody Target
    GJA1
  • Target Alternative Name
    Gap junction alpha-1 protein, Connexin-43, Cx43, Gap junction 43 kDa heart protein, GJA1, GJAL
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human, Mouse, Rat
  • Immunogen Sequence
    Synthesized peptide derived from human Connexin 43 around the phosphorylation site of S368
  • Accession
    P17302
  • Gene Id
    2697
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
  • Purification
    Affinity-chromatography using epitope-specific immunogen
  • Application
    WB, IHC, ELISA
  • Positive Control
    WB: HuvEc cell lysate
  • Application And Usages
    WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000
  • Description
    Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    Phospho-Connexin 43 (Ser368) Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    phosphorilated-Connexin 43 (Ser368) (antibody to-)
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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